Characterization of the adaptor protein ARH expression in the brain and ARH molecular interactions

Previously, pA134 was identified as one of the mRNAs present in the squid giant axon. Comparative sequence analyses revealed that the pA134 gene product manifested significant similarity to the mammalian lipoprotein receptor adaptor protein also known as ARH (autosomal recessive hypercholesterolemia...

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Veröffentlicht in:	Journal of neurochemistry 2007-11, Vol.103 (3), p.927-941
Hauptverfasser:	Mameza, Marie Germaine, Lockard, Jon M, Zamora, Eduardo, Hillefors, Mi, Lavina, Zeno Scotto, Kaplan, Barry B
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptor Proteins, Signal Transducing - genetics Adaptor Proteins, Signal Transducing - metabolism Animals axonal localization Axons - metabolism Axons - ultrastructure Biochemistry Biological and medical sciences Brain Brain - anatomy & histology Brain - metabolism Brain Chemistry - physiology Cell Line Cerebral circulation. Blood-brain barrier. Choroid plexus. Cerebrospinal fluid. Circumventricular organ. Meninges Cytoskeletal Proteins - metabolism Decapodiformes - genetics Decapodiformes - metabolism Disorders of blood lipids. Hyperlipoproteinemia Evolution, Molecular Fundamental and applied biological sciences. Psychology Ganglia, Sympathetic - metabolism Ganglia, Sympathetic - ultrastructure Genetics Humans lipoprotein Lipoproteins - metabolism Medical sciences Membrane Proteins - metabolism messenger RNA Metabolic diseases Mice Molecular Sequence Data mRNA Neurology Protein Binding - physiology Proteins Rats Rats, Sprague-Dawley Receptors, LDL - metabolism RNA, Messenger - metabolism Rodents Sequence Homology, Amino Acid sympathetic neurons Tumor Suppressor Proteins - metabolism Vertebrates: nervous system and sense organs yeast two hybrid screen
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