Influence of Applied Quantity of Sunscreen Products on the Sun Protection Factor – A Multicenter Study Organized by the DGK Task Force Sun Protection
It is often debated that the protection against solar-induced erythema under real conditions is dependent upon the amount of sunscreen applied. It is believed that when too little is applied a lower sun protection than indicated on the label will result. The aim of this study was to quantify this ef...
Gespeichert in:
| Veröffentlicht in: | Skin pharmacology and physiology 2007-01, Vol.20 (1), p.57-64 |
|---|---|
| Hauptverfasser: | , , , , , , , , , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 64 |
|---|---|
| container_issue | 1 |
| container_start_page | 57 |
| container_title | Skin pharmacology and physiology |
| container_volume | 20 |
| creator | Bimczok, R. Gers-Barlag, H. Mundt, C. Klette, E. Bielfeldt, S. Rudolph, T. Pflücker, F. Heinrich, U. Tronnier, H. Johncock, W. Klebon, B. Westenfelder, H. Flöβer-Müller, H. Jenni, K. Kockott, D. Lademann, J. Herzog, B. Rohr, M. |
| description | It is often debated that the protection against solar-induced erythema under real conditions is dependent upon the amount of sunscreen applied. It is believed that when too little is applied a lower sun protection than indicated on the label will result. The aim of this study was to quantify this effect. In this multicenter study, the influence of three different amounts (0.5, 1.0, 2.0 mg/cm 2 ) of three commercial sunscreen products in three reliable test centers was investigated according to the test protocol of The International Sun Protection Factor Test Method. The main result was a linear dependence of the SPF on the quantity applied. Taking into consideration the volunteer-specific variations, an exponential dependence of confidence interval of the in vivo SPF and amount applied was found. The highest amount applied (2.0 mg/cm 2 ) was linked to the lowest confidence intervals. Thus, from the point of view of producing reliable and reproducible in vivo results under laboratory conditions, the recommendation of this multicenter study is an application quantity of 2.0 mg/cm 2 . |
| doi_str_mv | 10.1159/000096173 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_proquest_miscellaneous_68385070</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1193245541</sourcerecordid><originalsourceid>FETCH-LOGICAL-c330t-9c837f68365056bb298ab490aae9548be487239c2a15b44f845864b8fbf7f4f83</originalsourceid><addsrcrecordid>eNpdkc1uEzEUhS0EoiWwYI2ELBZILFLs8fhnllEhpWpRQS3rke1cl2knduqfRVjxDix4vz5JHRIFqd5c-_i7R74-CL2m5IhS3n0kdXWCSvYEHVIhyJRzxp_u9408QC9SuiGkEZKK5-iASsK4bNgh-nvq3VjAW8DB4dlqNQ6wwN-L9nnI6412WXyyEcDjbzEsis0JB4_zT9jcbLQMNg9VmmubQ8T3v__gGf5axjxY8BkivsxlscYX8Vr74Vd1N-t_7Z9OzvCVTrd4HqJ97PYSPXN6TPBqVyfox_zz1fGX6fnFyenx7HxqGSN52lnFpBOKCU64MKbplDZtR7SGjrfKQKvqmJ1tNOWmbZ1quRKtUc446eqRTdD7re8qhrsCKffLIVkYR-0hlNRXa8VJ_a4JevcIvAkl-vq2vml4IwSTskIftpCNIaUIrl_FYanjuqek30TV76Oq7NudYTFLWPwnd9lU4M0WuNXxGuIe2LY_ANkTl6E</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>225266377</pqid></control><display><type>article</type><title>Influence of Applied Quantity of Sunscreen Products on the Sun Protection Factor – A Multicenter Study Organized by the DGK Task Force Sun Protection</title><source>MEDLINE</source><source>Karger Journals Complete</source><source>Alma/SFX Local Collection</source><creator>Bimczok, R. ; Gers-Barlag, H. ; Mundt, C. ; Klette, E. ; Bielfeldt, S. ; Rudolph, T. ; Pflücker, F. ; Heinrich, U. ; Tronnier, H. ; Johncock, W. ; Klebon, B. ; Westenfelder, H. ; Flöβer-Müller, H. ; Jenni, K. ; Kockott, D. ; Lademann, J. ; Herzog, B. ; Rohr, M.</creator><creatorcontrib>Bimczok, R. ; Gers-Barlag, H. ; Mundt, C. ; Klette, E. ; Bielfeldt, S. ; Rudolph, T. ; Pflücker, F. ; Heinrich, U. ; Tronnier, H. ; Johncock, W. ; Klebon, B. ; Westenfelder, H. ; Flöβer-Müller, H. ; Jenni, K. ; Kockott, D. ; Lademann, J. ; Herzog, B. ; Rohr, M.</creatorcontrib><description>It is often debated that the protection against solar-induced erythema under real conditions is dependent upon the amount of sunscreen applied. It is believed that when too little is applied a lower sun protection than indicated on the label will result. The aim of this study was to quantify this effect. In this multicenter study, the influence of three different amounts (0.5, 1.0, 2.0 mg/cm 2 ) of three commercial sunscreen products in three reliable test centers was investigated according to the test protocol of The International Sun Protection Factor Test Method. The main result was a linear dependence of the SPF on the quantity applied. Taking into consideration the volunteer-specific variations, an exponential dependence of confidence interval of the in vivo SPF and amount applied was found. The highest amount applied (2.0 mg/cm 2 ) was linked to the lowest confidence intervals. Thus, from the point of view of producing reliable and reproducible in vivo results under laboratory conditions, the recommendation of this multicenter study is an application quantity of 2.0 mg/cm 2 .</description><identifier>ISSN: 1660-5527</identifier><identifier>EISSN: 1660-5535</identifier><identifier>DOI: 10.1159/000096173</identifier><identifier>PMID: 17035723</identifier><language>eng</language><publisher>Basel, Switzerland: S. Karger AG</publisher><subject>Confidence Intervals ; Dose-Response Relationship, Drug ; Erythema - etiology ; Erythema - prevention & control ; Humans ; Linear Models ; Original Paper ; Sunscreening Agents - administration & dosage ; Sunscreening Agents - therapeutic use ; Ultraviolet Rays - adverse effects</subject><ispartof>Skin pharmacology and physiology, 2007-01, Vol.20 (1), p.57-64</ispartof><rights>2007 S. Karger AG, Basel</rights><rights>Copyright (c) 2007 S. Karger AG, Basel</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c330t-9c837f68365056bb298ab490aae9548be487239c2a15b44f845864b8fbf7f4f83</citedby><cites>FETCH-LOGICAL-c330t-9c837f68365056bb298ab490aae9548be487239c2a15b44f845864b8fbf7f4f83</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,2429,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/17035723$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Bimczok, R.</creatorcontrib><creatorcontrib>Gers-Barlag, H.</creatorcontrib><creatorcontrib>Mundt, C.</creatorcontrib><creatorcontrib>Klette, E.</creatorcontrib><creatorcontrib>Bielfeldt, S.</creatorcontrib><creatorcontrib>Rudolph, T.</creatorcontrib><creatorcontrib>Pflücker, F.</creatorcontrib><creatorcontrib>Heinrich, U.</creatorcontrib><creatorcontrib>Tronnier, H.</creatorcontrib><creatorcontrib>Johncock, W.</creatorcontrib><creatorcontrib>Klebon, B.</creatorcontrib><creatorcontrib>Westenfelder, H.</creatorcontrib><creatorcontrib>Flöβer-Müller, H.</creatorcontrib><creatorcontrib>Jenni, K.</creatorcontrib><creatorcontrib>Kockott, D.</creatorcontrib><creatorcontrib>Lademann, J.</creatorcontrib><creatorcontrib>Herzog, B.</creatorcontrib><creatorcontrib>Rohr, M.</creatorcontrib><title>Influence of Applied Quantity of Sunscreen Products on the Sun Protection Factor – A Multicenter Study Organized by the DGK Task Force Sun Protection</title><title>Skin pharmacology and physiology</title><addtitle>Skin Pharmacol Physiol</addtitle><description>It is often debated that the protection against solar-induced erythema under real conditions is dependent upon the amount of sunscreen applied. It is believed that when too little is applied a lower sun protection than indicated on the label will result. The aim of this study was to quantify this effect. In this multicenter study, the influence of three different amounts (0.5, 1.0, 2.0 mg/cm 2 ) of three commercial sunscreen products in three reliable test centers was investigated according to the test protocol of The International Sun Protection Factor Test Method. The main result was a linear dependence of the SPF on the quantity applied. Taking into consideration the volunteer-specific variations, an exponential dependence of confidence interval of the in vivo SPF and amount applied was found. The highest amount applied (2.0 mg/cm 2 ) was linked to the lowest confidence intervals. Thus, from the point of view of producing reliable and reproducible in vivo results under laboratory conditions, the recommendation of this multicenter study is an application quantity of 2.0 mg/cm 2 .</description><subject>Confidence Intervals</subject><subject>Dose-Response Relationship, Drug</subject><subject>Erythema - etiology</subject><subject>Erythema - prevention & control</subject><subject>Humans</subject><subject>Linear Models</subject><subject>Original Paper</subject><subject>Sunscreening Agents - administration & dosage</subject><subject>Sunscreening Agents - therapeutic use</subject><subject>Ultraviolet Rays - adverse effects</subject><issn>1660-5527</issn><issn>1660-5535</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2007</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNpdkc1uEzEUhS0EoiWwYI2ELBZILFLs8fhnllEhpWpRQS3rke1cl2knduqfRVjxDix4vz5JHRIFqd5c-_i7R74-CL2m5IhS3n0kdXWCSvYEHVIhyJRzxp_u9408QC9SuiGkEZKK5-iASsK4bNgh-nvq3VjAW8DB4dlqNQ6wwN-L9nnI6412WXyyEcDjbzEsis0JB4_zT9jcbLQMNg9VmmubQ8T3v__gGf5axjxY8BkivsxlscYX8Vr74Vd1N-t_7Z9OzvCVTrd4HqJ97PYSPXN6TPBqVyfox_zz1fGX6fnFyenx7HxqGSN52lnFpBOKCU64MKbplDZtR7SGjrfKQKvqmJ1tNOWmbZ1quRKtUc446eqRTdD7re8qhrsCKffLIVkYR-0hlNRXa8VJ_a4JevcIvAkl-vq2vml4IwSTskIftpCNIaUIrl_FYanjuqek30TV76Oq7NudYTFLWPwnd9lU4M0WuNXxGuIe2LY_ANkTl6E</recordid><startdate>20070101</startdate><enddate>20070101</enddate><creator>Bimczok, R.</creator><creator>Gers-Barlag, H.</creator><creator>Mundt, C.</creator><creator>Klette, E.</creator><creator>Bielfeldt, S.</creator><creator>Rudolph, T.</creator><creator>Pflücker, F.</creator><creator>Heinrich, U.</creator><creator>Tronnier, H.</creator><creator>Johncock, W.</creator><creator>Klebon, B.</creator><creator>Westenfelder, H.</creator><creator>Flöβer-Müller, H.</creator><creator>Jenni, K.</creator><creator>Kockott, D.</creator><creator>Lademann, J.</creator><creator>Herzog, B.</creator><creator>Rohr, M.</creator><general>S. Karger AG</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QO</scope><scope>7U7</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FD</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>C1K</scope><scope>CCPQU</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope></search><sort><creationdate>20070101</creationdate><title>Influence of Applied Quantity of Sunscreen Products on the Sun Protection Factor – A Multicenter Study Organized by the DGK Task Force Sun Protection</title><author>Bimczok, R. ; Gers-Barlag, H. ; Mundt, C. ; Klette, E. ; Bielfeldt, S. ; Rudolph, T. ; Pflücker, F. ; Heinrich, U. ; Tronnier, H. ; Johncock, W. ; Klebon, B. ; Westenfelder, H. ; Flöβer-Müller, H. ; Jenni, K. ; Kockott, D. ; Lademann, J. ; Herzog, B. ; Rohr, M.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c330t-9c837f68365056bb298ab490aae9548be487239c2a15b44f845864b8fbf7f4f83</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2007</creationdate><topic>Confidence Intervals</topic><topic>Dose-Response Relationship, Drug</topic><topic>Erythema - etiology</topic><topic>Erythema - prevention & control</topic><topic>Humans</topic><topic>Linear Models</topic><topic>Original Paper</topic><topic>Sunscreening Agents - administration & dosage</topic><topic>Sunscreening Agents - therapeutic use</topic><topic>Ultraviolet Rays - adverse effects</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Bimczok, R.</creatorcontrib><creatorcontrib>Gers-Barlag, H.</creatorcontrib><creatorcontrib>Mundt, C.</creatorcontrib><creatorcontrib>Klette, E.</creatorcontrib><creatorcontrib>Bielfeldt, S.</creatorcontrib><creatorcontrib>Rudolph, T.</creatorcontrib><creatorcontrib>Pflücker, F.</creatorcontrib><creatorcontrib>Heinrich, U.</creatorcontrib><creatorcontrib>Tronnier, H.</creatorcontrib><creatorcontrib>Johncock, W.</creatorcontrib><creatorcontrib>Klebon, B.</creatorcontrib><creatorcontrib>Westenfelder, H.</creatorcontrib><creatorcontrib>Flöβer-Müller, H.</creatorcontrib><creatorcontrib>Jenni, K.</creatorcontrib><creatorcontrib>Kockott, D.</creatorcontrib><creatorcontrib>Lademann, J.</creatorcontrib><creatorcontrib>Herzog, B.</creatorcontrib><creatorcontrib>Rohr, M.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Biotechnology Research Abstracts</collection><collection>Toxicology Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Technology Research Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>Skin pharmacology and physiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Bimczok, R.</au><au>Gers-Barlag, H.</au><au>Mundt, C.</au><au>Klette, E.</au><au>Bielfeldt, S.</au><au>Rudolph, T.</au><au>Pflücker, F.</au><au>Heinrich, U.</au><au>Tronnier, H.</au><au>Johncock, W.</au><au>Klebon, B.</au><au>Westenfelder, H.</au><au>Flöβer-Müller, H.</au><au>Jenni, K.</au><au>Kockott, D.</au><au>Lademann, J.</au><au>Herzog, B.</au><au>Rohr, M.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Influence of Applied Quantity of Sunscreen Products on the Sun Protection Factor – A Multicenter Study Organized by the DGK Task Force Sun Protection</atitle><jtitle>Skin pharmacology and physiology</jtitle><addtitle>Skin Pharmacol Physiol</addtitle><date>2007-01-01</date><risdate>2007</risdate><volume>20</volume><issue>1</issue><spage>57</spage><epage>64</epage><pages>57-64</pages><issn>1660-5527</issn><eissn>1660-5535</eissn><abstract>It is often debated that the protection against solar-induced erythema under real conditions is dependent upon the amount of sunscreen applied. It is believed that when too little is applied a lower sun protection than indicated on the label will result. The aim of this study was to quantify this effect. In this multicenter study, the influence of three different amounts (0.5, 1.0, 2.0 mg/cm 2 ) of three commercial sunscreen products in three reliable test centers was investigated according to the test protocol of The International Sun Protection Factor Test Method. The main result was a linear dependence of the SPF on the quantity applied. Taking into consideration the volunteer-specific variations, an exponential dependence of confidence interval of the in vivo SPF and amount applied was found. The highest amount applied (2.0 mg/cm 2 ) was linked to the lowest confidence intervals. Thus, from the point of view of producing reliable and reproducible in vivo results under laboratory conditions, the recommendation of this multicenter study is an application quantity of 2.0 mg/cm 2 .</abstract><cop>Basel, Switzerland</cop><pub>S. Karger AG</pub><pmid>17035723</pmid><doi>10.1159/000096173</doi><tpages>8</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1660-5527 |
| ispartof | Skin pharmacology and physiology, 2007-01, Vol.20 (1), p.57-64 |
| issn | 1660-5527 1660-5535 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_68385070 |
| source | MEDLINE; Karger Journals Complete; Alma/SFX Local Collection |
| subjects | Confidence Intervals Dose-Response Relationship, Drug Erythema - etiology Erythema - prevention & control Humans Linear Models Original Paper Sunscreening Agents - administration & dosage Sunscreening Agents - therapeutic use Ultraviolet Rays - adverse effects |
| title | Influence of Applied Quantity of Sunscreen Products on the Sun Protection Factor – A Multicenter Study Organized by the DGK Task Force Sun Protection |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-27T07%3A36%3A26IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Influence%20of%20Applied%20Quantity%20of%20Sunscreen%20Products%20on%20the%20Sun%20Protection%20Factor%20%E2%80%93%20A%20Multicenter%20Study%20Organized%20by%20the%20DGK%20Task%20Force%20Sun%20Protection&rft.jtitle=Skin%20pharmacology%20and%20physiology&rft.au=Bimczok,%20R.&rft.date=2007-01-01&rft.volume=20&rft.issue=1&rft.spage=57&rft.epage=64&rft.pages=57-64&rft.issn=1660-5527&rft.eissn=1660-5535&rft_id=info:doi/10.1159/000096173&rft_dat=%3Cproquest_pubme%3E1193245541%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=225266377&rft_id=info:pmid/17035723&rfr_iscdi=true |