Concord grape juice attenuates platelet aggregation, serum cholesterol and development of atheroma in hypercholesterolemic rabbits

Abstract Intake of Concord grape juice (CGJ), rich in polyphenolics, inhibits platelet aggregation (PA), a risk factor for cardiovascular disease (CVD), in normocholesterolemic animals and humans. It is unclear whether CGJ can attenuate hypercholesterolemia-enhanced PA. The effects of daily CGJ cons...

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Veröffentlicht in:	Atherosclerosis 2007-01, Vol.190 (1), p.135-142
Hauptverfasser:	Shanmuganayagam, Dhanansayan, Warner, Thomas F, Krueger, Christian G, Reed, Jess D, Folts, John D
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Aorta - pathology Atherosclerosis Atherosclerosis (general aspects, experimental research) Atherosclerosis - drug therapy Atherosclerosis - pathology Atherosclerosis - prevention & control Biological and medical sciences Blood and lymphatic vessels Blood coagulation. Blood cells Blood Pressure - drug effects Blood vessels and receptors Body Weight - drug effects Cardiology. Vascular system Cardiovascular Cholesterol Cholesterol - blood Flavonoids - pharmacology Fundamental and applied biological sciences. Psychology Grape juice Hypercholesterolemia Hypercholesterolemia - drug therapy Hypercholesterolemia - pathology Male Medical sciences Molecular and cellular biology Phenols - pharmacology Phytotherapy Platelet Platelet Aggregation - drug effects Platelets Polyphenolics Polyphenols Rabbits Vertebrates: cardiovascular system Vitis
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