Homeobox gene Dlx3 is regulated by p63 during ectoderm development: relevance in the pathogenesis of ectodermal dysplasias

Ectodermal dysplasias (EDs) are a group of human pathological conditions characterized by anomalies in organs derived from epithelial-mesenchymal interactions during development. Dlx3 and p63 act as part of the transcriptional regulatory pathways relevant in ectoderm derivatives, and autosomal mutat...

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Veröffentlicht in:	Development (Cambridge) 2007-01, Vol.134 (1), p.13-18
Hauptverfasser:	Radoja, Nadezda, Guerrini, Luisa, Lo Iacono, Nadia, Merlo, Giorgio R., Costanzo, Antonio, Weinberg, Wendy C., La Mantia, Girolama, Calabrò, Viola, Morasso, Maria I.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Line Cell Line, Tumor Chromatin Immunoprecipitation Ectodermal Dysplasia - etiology Ectodermal Dysplasia - genetics Gene Expression Regulation, Developmental Genes, Homeobox Homeodomain Proteins - genetics Humans Immunohistochemistry Keratinocytes - metabolism Male Mice Mutation Osteosarcoma - pathology Phosphoproteins - genetics Promoter Regions, Genetic Protein Structure, Tertiary Skin - cytology Trans-Activators - genetics Transcription Factors - genetics Transcription, Genetic
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