Methanol extract of the seaweed Gloiopeltis furcata induces G2/M arrest and inhibits cyclooxygenase-2 activity in human hepatocarcinoma HepG2 cells

It was previously reported that a methanol extract of Gloiopeltis furcata (MEGF), a kind of edible seaweed, inhibited the growth of several human cancer cell lines. In the present study, the effect of MEGF on the growth of human hepatocarcinoma HepG2 cells and its effect on the cyclooxygenases (COXs...

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Veröffentlicht in:	Phytotherapy research 2007-01, Vol.21 (1), p.52-57
Hauptverfasser:	Bae, Song Ja, Choi, Yung Hyun
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic Agents, Phytogenic - administration & dosage Antineoplastic Agents, Phytogenic - pharmacology Antineoplastic Agents, Phytogenic - therapeutic use Biological and medical sciences Cell Cycle - drug effects Cell Line, Tumor - drug effects COX-2 Cyclooxygenase 2 - biosynthesis Cyclooxygenase 2 - genetics Cyclooxygenase Inhibitors - administration & dosage Cyclooxygenase Inhibitors - pharmacology Cyclooxygenase Inhibitors - therapeutic use DNA Primers Dose-Response Relationship, Drug Flow Cytometry G2/M arrest General pharmacology Gloiopeltis furcata HepG2 Humans Medical sciences p21 Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments Phytotherapy Plant Extracts - administration & dosage Plant Extracts - pharmacology Plant Extracts - therapeutic use Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger - analysis Seaweed
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