Small hepatic lesions found on single-phase helical CT in patients with malignancy: Diagnostic capability of breath-hold, multisection fluid-attenuated inversion-recovery (FLAIR) MR imaging using a half-fourier acquisition single-shot turbo spin-echo (HASTE) sequence
Purpose To evaluate the diagnostic capability of breath‐hold, multisection fluid‐attenuated inversion‐recovery (FLAIR) imaging using a half‐Fourier acquisition single‐shot turbo spin‐echo (HASTE) sequence in combination with T2‐weighted fast spin‐echo (FSE) magnetic resonance (MR) sequences for smal...
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| Veröffentlicht in: | Journal of magnetic resonance imaging 2007-01, Vol.25 (1), p.129-136 |
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| container_title | Journal of magnetic resonance imaging |
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| creator | Sasaki, Katsumi Ito, Katsuyoshi Fujita, Takeshi Shimizu, Ayame Yasui, Masayasu Hayashida, Minoru Tanabe, Masahiro Matsunaga, Naofumi |
| description | Purpose
To evaluate the diagnostic capability of breath‐hold, multisection fluid‐attenuated inversion‐recovery (FLAIR) imaging using a half‐Fourier acquisition single‐shot turbo spin‐echo (HASTE) sequence in combination with T2‐weighted fast spin‐echo (FSE) magnetic resonance (MR) sequences for small hepatic lesions found on CT in patients with malignancy.
Materials and Methods
This study included 48 patients with extrahepatic malignancy who underwent both CT and MR examinations. There were a total of 112 small hepatic lesions (73 cysts and 39 liver metastases, |
| doi_str_mv | 10.1002/jmri.20797 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_68376738</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>19695507</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4327-687e5e98c0af358bc0af550e1d143b16bcee6e81d738e9c61f6d8f51a92ffe013</originalsourceid><addsrcrecordid>eNqFkl9v0zAUxQMCsVF44QOg-4Q2RIadNP94q8rWFm0gdUVIvESOc9N4c-zMdhj99jhrgTd4uvfhd849tk4QvKLkjBISvb_pjDiLSFZkj4NjmkRRGCV5-sTvJIlDmpPsKHhu7Q0hpCimybPgiGYeI0l0_Ghy3TEpocWeOcFBohVaWWj0oGrQCqxQW4lh3zKLnpKCMwnzDQgFowKVs3AvXAveRmwVU3z3AT4KtlXajoac9awSUrgd6AYqg8y1Yatl_Q66QTphkTt_ERo5iDpkzqEamMPaH_iBZgwTGuTa7zs4ubicrdancLUG0bGtTwbDmA8YtEw2oQ9tBBpg_G4QVjz4HvLbVjtwg6k02F6oEHmr4WQ5u96cn4LFuwEVxxfB04ZJiy8PcxJ8vTjfzJfh5ZfFaj67DPk0jrIwzTNMsMg5YU2c5NU4k4Qgrek0rmhaccQUc1pncY4FT2mT1nmTUFZETYOExpPgzd63N9pftq7shOUoJVOoB1umeZylXvxfkBZp4S9nHny7B7nR1hpsyt74LzK7kpJy7Eg5dqR86IiHXx9ch6rD-i96KIUH6B64FxJ3_7AqP12tV79Nw71GWIc__2iYuS39U7Kk_PZ5UX7P0-lykdFyHf8CMI3byQ</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>19695507</pqid></control><display><type>article</type><title>Small hepatic lesions found on single-phase helical CT in patients with malignancy: Diagnostic capability of breath-hold, multisection fluid-attenuated inversion-recovery (FLAIR) MR imaging using a half-fourier acquisition single-shot turbo spin-echo (HASTE) sequence</title><source>MEDLINE</source><source>Wiley Journals</source><source>Wiley Online Library Free Content</source><creator>Sasaki, Katsumi ; Ito, Katsuyoshi ; Fujita, Takeshi ; Shimizu, Ayame ; Yasui, Masayasu ; Hayashida, Minoru ; Tanabe, Masahiro ; Matsunaga, Naofumi</creator><creatorcontrib>Sasaki, Katsumi ; Ito, Katsuyoshi ; Fujita, Takeshi ; Shimizu, Ayame ; Yasui, Masayasu ; Hayashida, Minoru ; Tanabe, Masahiro ; Matsunaga, Naofumi</creatorcontrib><description>Purpose
To evaluate the diagnostic capability of breath‐hold, multisection fluid‐attenuated inversion‐recovery (FLAIR) imaging using a half‐Fourier acquisition single‐shot turbo spin‐echo (HASTE) sequence in combination with T2‐weighted fast spin‐echo (FSE) magnetic resonance (MR) sequences for small hepatic lesions found on CT in patients with malignancy.
Materials and Methods
This study included 48 patients with extrahepatic malignancy who underwent both CT and MR examinations. There were a total of 112 small hepatic lesions (73 cysts and 39 liver metastases, <2 cm in diameter) that showed low attenuation on enhanced CT. Three radiologists independently reviewed the CT and MR (FLAIR‐HASTE and T2‐weighted FSE) images and assigned a confidence level to their evaluation (cyst or metastasis) on a five‐point scale.
Results
All three reviewers were significantly better able (P < 0.05) to differentiate small hepatic cyst from liver metastasis with combined FLAIR‐HASTE and T2‐weighted FSE images (Az values = 0.997–0.999) than with CT (0.917–0.932). The mean values of sensitivity, specificity, and accuracy were significantly higher (P < 0.001) for T2‐weighted FSE with FLAIR‐HASTE (96.6%, 96.8%, and 96.7%, respectively) than for CT (76.9%, 61.6%, and 67.3%, respectively). A confident diagnosis was rendered in 12 of 112 lesions (10.7%) on the basis of CT, and this rate increased to 83 of 112 (74.1%) on the basis of T2‐weighted FSE and FLAIR‐HASTE imaging.
Conclusion
FLAIR‐HASTE is considered to be an effective sequence for differentiating hepatic cysts from liver metastases without the use of a contrast agent. With FLAIR‐HASTE one can confidently diagnose small hepatic lesions found on CT in patients with a malignancy. J. Magn. Reson. Imaging 2007. © 2006 Wiley‐Liss, Inc.</description><identifier>ISSN: 1053-1807</identifier><identifier>EISSN: 1522-2586</identifier><identifier>DOI: 10.1002/jmri.20797</identifier><identifier>PMID: 17152052</identifier><language>eng</language><publisher>Hoboken: Wiley Subscription Services, Inc., A Wiley Company</publisher><subject>Adolescent ; Adult ; Aged ; Aged, 80 and over ; Contrast Media ; Diagnosis, Differential ; Female ; FLAIR-HASTE ; hepatic cyst ; Humans ; Iopamidol ; liver CT ; Liver Diseases - diagnosis ; Liver Diseases - diagnostic imaging ; liver metastasis ; liver MR ; Magnetic Resonance Imaging - methods ; Male ; Middle Aged ; Sensitivity and Specificity ; Tomography, Spiral Computed</subject><ispartof>Journal of magnetic resonance imaging, 2007-01, Vol.25 (1), p.129-136</ispartof><rights>Copyright © 2006 Wiley‐Liss, Inc.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4327-687e5e98c0af358bc0af550e1d143b16bcee6e81d738e9c61f6d8f51a92ffe013</citedby><cites>FETCH-LOGICAL-c4327-687e5e98c0af358bc0af550e1d143b16bcee6e81d738e9c61f6d8f51a92ffe013</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fjmri.20797$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fjmri.20797$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1417,1433,27924,27925,45574,45575,46409,46833</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/17152052$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Sasaki, Katsumi</creatorcontrib><creatorcontrib>Ito, Katsuyoshi</creatorcontrib><creatorcontrib>Fujita, Takeshi</creatorcontrib><creatorcontrib>Shimizu, Ayame</creatorcontrib><creatorcontrib>Yasui, Masayasu</creatorcontrib><creatorcontrib>Hayashida, Minoru</creatorcontrib><creatorcontrib>Tanabe, Masahiro</creatorcontrib><creatorcontrib>Matsunaga, Naofumi</creatorcontrib><title>Small hepatic lesions found on single-phase helical CT in patients with malignancy: Diagnostic capability of breath-hold, multisection fluid-attenuated inversion-recovery (FLAIR) MR imaging using a half-fourier acquisition single-shot turbo spin-echo (HASTE) sequence</title><title>Journal of magnetic resonance imaging</title><addtitle>J. Magn. Reson. Imaging</addtitle><description>Purpose
To evaluate the diagnostic capability of breath‐hold, multisection fluid‐attenuated inversion‐recovery (FLAIR) imaging using a half‐Fourier acquisition single‐shot turbo spin‐echo (HASTE) sequence in combination with T2‐weighted fast spin‐echo (FSE) magnetic resonance (MR) sequences for small hepatic lesions found on CT in patients with malignancy.
Materials and Methods
This study included 48 patients with extrahepatic malignancy who underwent both CT and MR examinations. There were a total of 112 small hepatic lesions (73 cysts and 39 liver metastases, <2 cm in diameter) that showed low attenuation on enhanced CT. Three radiologists independently reviewed the CT and MR (FLAIR‐HASTE and T2‐weighted FSE) images and assigned a confidence level to their evaluation (cyst or metastasis) on a five‐point scale.
Results
All three reviewers were significantly better able (P < 0.05) to differentiate small hepatic cyst from liver metastasis with combined FLAIR‐HASTE and T2‐weighted FSE images (Az values = 0.997–0.999) than with CT (0.917–0.932). The mean values of sensitivity, specificity, and accuracy were significantly higher (P < 0.001) for T2‐weighted FSE with FLAIR‐HASTE (96.6%, 96.8%, and 96.7%, respectively) than for CT (76.9%, 61.6%, and 67.3%, respectively). A confident diagnosis was rendered in 12 of 112 lesions (10.7%) on the basis of CT, and this rate increased to 83 of 112 (74.1%) on the basis of T2‐weighted FSE and FLAIR‐HASTE imaging.
Conclusion
FLAIR‐HASTE is considered to be an effective sequence for differentiating hepatic cysts from liver metastases without the use of a contrast agent. With FLAIR‐HASTE one can confidently diagnose small hepatic lesions found on CT in patients with a malignancy. J. Magn. Reson. Imaging 2007. © 2006 Wiley‐Liss, Inc.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Contrast Media</subject><subject>Diagnosis, Differential</subject><subject>Female</subject><subject>FLAIR-HASTE</subject><subject>hepatic cyst</subject><subject>Humans</subject><subject>Iopamidol</subject><subject>liver CT</subject><subject>Liver Diseases - diagnosis</subject><subject>Liver Diseases - diagnostic imaging</subject><subject>liver metastasis</subject><subject>liver MR</subject><subject>Magnetic Resonance Imaging - methods</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Sensitivity and Specificity</subject><subject>Tomography, Spiral Computed</subject><issn>1053-1807</issn><issn>1522-2586</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2007</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkl9v0zAUxQMCsVF44QOg-4Q2RIadNP94q8rWFm0gdUVIvESOc9N4c-zMdhj99jhrgTd4uvfhd849tk4QvKLkjBISvb_pjDiLSFZkj4NjmkRRGCV5-sTvJIlDmpPsKHhu7Q0hpCimybPgiGYeI0l0_Ghy3TEpocWeOcFBohVaWWj0oGrQCqxQW4lh3zKLnpKCMwnzDQgFowKVs3AvXAveRmwVU3z3AT4KtlXajoac9awSUrgd6AYqg8y1Yatl_Q66QTphkTt_ERo5iDpkzqEamMPaH_iBZgwTGuTa7zs4ubicrdancLUG0bGtTwbDmA8YtEw2oQ9tBBpg_G4QVjz4HvLbVjtwg6k02F6oEHmr4WQ5u96cn4LFuwEVxxfB04ZJiy8PcxJ8vTjfzJfh5ZfFaj67DPk0jrIwzTNMsMg5YU2c5NU4k4Qgrek0rmhaccQUc1pncY4FT2mT1nmTUFZETYOExpPgzd63N9pftq7shOUoJVOoB1umeZylXvxfkBZp4S9nHny7B7nR1hpsyt74LzK7kpJy7Eg5dqR86IiHXx9ch6rD-i96KIUH6B64FxJ3_7AqP12tV79Nw71GWIc__2iYuS39U7Kk_PZ5UX7P0-lykdFyHf8CMI3byQ</recordid><startdate>200701</startdate><enddate>200701</enddate><creator>Sasaki, Katsumi</creator><creator>Ito, Katsuyoshi</creator><creator>Fujita, Takeshi</creator><creator>Shimizu, Ayame</creator><creator>Yasui, Masayasu</creator><creator>Hayashida, Minoru</creator><creator>Tanabe, Masahiro</creator><creator>Matsunaga, Naofumi</creator><general>Wiley Subscription Services, Inc., A Wiley Company</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QO</scope><scope>8FD</scope><scope>FR3</scope><scope>P64</scope><scope>7X8</scope></search><sort><creationdate>200701</creationdate><title>Small hepatic lesions found on single-phase helical CT in patients with malignancy: Diagnostic capability of breath-hold, multisection fluid-attenuated inversion-recovery (FLAIR) MR imaging using a half-fourier acquisition single-shot turbo spin-echo (HASTE) sequence</title><author>Sasaki, Katsumi ; Ito, Katsuyoshi ; Fujita, Takeshi ; Shimizu, Ayame ; Yasui, Masayasu ; Hayashida, Minoru ; Tanabe, Masahiro ; Matsunaga, Naofumi</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4327-687e5e98c0af358bc0af550e1d143b16bcee6e81d738e9c61f6d8f51a92ffe013</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2007</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Contrast Media</topic><topic>Diagnosis, Differential</topic><topic>Female</topic><topic>FLAIR-HASTE</topic><topic>hepatic cyst</topic><topic>Humans</topic><topic>Iopamidol</topic><topic>liver CT</topic><topic>Liver Diseases - diagnosis</topic><topic>Liver Diseases - diagnostic imaging</topic><topic>liver metastasis</topic><topic>liver MR</topic><topic>Magnetic Resonance Imaging - methods</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Sensitivity and Specificity</topic><topic>Tomography, Spiral Computed</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Sasaki, Katsumi</creatorcontrib><creatorcontrib>Ito, Katsuyoshi</creatorcontrib><creatorcontrib>Fujita, Takeshi</creatorcontrib><creatorcontrib>Shimizu, Ayame</creatorcontrib><creatorcontrib>Yasui, Masayasu</creatorcontrib><creatorcontrib>Hayashida, Minoru</creatorcontrib><creatorcontrib>Tanabe, Masahiro</creatorcontrib><creatorcontrib>Matsunaga, Naofumi</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Biotechnology Research Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of magnetic resonance imaging</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Sasaki, Katsumi</au><au>Ito, Katsuyoshi</au><au>Fujita, Takeshi</au><au>Shimizu, Ayame</au><au>Yasui, Masayasu</au><au>Hayashida, Minoru</au><au>Tanabe, Masahiro</au><au>Matsunaga, Naofumi</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Small hepatic lesions found on single-phase helical CT in patients with malignancy: Diagnostic capability of breath-hold, multisection fluid-attenuated inversion-recovery (FLAIR) MR imaging using a half-fourier acquisition single-shot turbo spin-echo (HASTE) sequence</atitle><jtitle>Journal of magnetic resonance imaging</jtitle><addtitle>J. Magn. Reson. Imaging</addtitle><date>2007-01</date><risdate>2007</risdate><volume>25</volume><issue>1</issue><spage>129</spage><epage>136</epage><pages>129-136</pages><issn>1053-1807</issn><eissn>1522-2586</eissn><abstract>Purpose
To evaluate the diagnostic capability of breath‐hold, multisection fluid‐attenuated inversion‐recovery (FLAIR) imaging using a half‐Fourier acquisition single‐shot turbo spin‐echo (HASTE) sequence in combination with T2‐weighted fast spin‐echo (FSE) magnetic resonance (MR) sequences for small hepatic lesions found on CT in patients with malignancy.
Materials and Methods
This study included 48 patients with extrahepatic malignancy who underwent both CT and MR examinations. There were a total of 112 small hepatic lesions (73 cysts and 39 liver metastases, <2 cm in diameter) that showed low attenuation on enhanced CT. Three radiologists independently reviewed the CT and MR (FLAIR‐HASTE and T2‐weighted FSE) images and assigned a confidence level to their evaluation (cyst or metastasis) on a five‐point scale.
Results
All three reviewers were significantly better able (P < 0.05) to differentiate small hepatic cyst from liver metastasis with combined FLAIR‐HASTE and T2‐weighted FSE images (Az values = 0.997–0.999) than with CT (0.917–0.932). The mean values of sensitivity, specificity, and accuracy were significantly higher (P < 0.001) for T2‐weighted FSE with FLAIR‐HASTE (96.6%, 96.8%, and 96.7%, respectively) than for CT (76.9%, 61.6%, and 67.3%, respectively). A confident diagnosis was rendered in 12 of 112 lesions (10.7%) on the basis of CT, and this rate increased to 83 of 112 (74.1%) on the basis of T2‐weighted FSE and FLAIR‐HASTE imaging.
Conclusion
FLAIR‐HASTE is considered to be an effective sequence for differentiating hepatic cysts from liver metastases without the use of a contrast agent. With FLAIR‐HASTE one can confidently diagnose small hepatic lesions found on CT in patients with a malignancy. J. Magn. Reson. Imaging 2007. © 2006 Wiley‐Liss, Inc.</abstract><cop>Hoboken</cop><pub>Wiley Subscription Services, Inc., A Wiley Company</pub><pmid>17152052</pmid><doi>10.1002/jmri.20797</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
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| ispartof | Journal of magnetic resonance imaging, 2007-01, Vol.25 (1), p.129-136 |
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| subjects | Adolescent Adult Aged Aged, 80 and over Contrast Media Diagnosis, Differential Female FLAIR-HASTE hepatic cyst Humans Iopamidol liver CT Liver Diseases - diagnosis Liver Diseases - diagnostic imaging liver metastasis liver MR Magnetic Resonance Imaging - methods Male Middle Aged Sensitivity and Specificity Tomography, Spiral Computed |
| title | Small hepatic lesions found on single-phase helical CT in patients with malignancy: Diagnostic capability of breath-hold, multisection fluid-attenuated inversion-recovery (FLAIR) MR imaging using a half-fourier acquisition single-shot turbo spin-echo (HASTE) sequence |
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