Increased Expression of Wnt5a in Psoriatic Plaques

Psoriasis vulgaris is characterized by hyperproliferation and incomplete terminal differentiation of epidermal keratinocytes. Despite the established role of Wnt pathways in the regulation of stem cell proliferation and differentiation, they have not yet been associated with the pathophysiology of p...

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Veröffentlicht in:	Journal of investigative dermatology 2007-01, Vol.127 (1), p.163-169
Hauptverfasser:	Reischl, Joachim, Schwenke, Susanne, Beekman, Johanna M., Mrowietz, Ulrich, Stürzebecher, Steffen, Heubach, Jürgen F.
Format:	Artikel
Sprache:	eng
Schlagworte:	beta Catenin - physiology Biological and medical sciences Biopsy Calcium - metabolism Dermatology Female Gene Expression Profiling Humans Inflammation - etiology Low Density Lipoprotein Receptor-Related Protein-1 - genetics Male Medical sciences Oligonucleotide Array Sequence Analysis Proto-Oncogene Proteins - genetics Proto-Oncogene Proteins - physiology Psoriasis - etiology Psoriasis - genetics Psoriasis. Parapsoriasis. Lichen Reverse Transcriptase Polymerase Chain Reaction Signal Transduction Skin - metabolism Wnt Proteins - genetics Wnt Proteins - physiology Wnt-5a Protein
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