Species differences in the localization of soluble guanylyl cyclase subunits in monkey and rat brain

Nitric oxide (NO) exerts most of its physiological effects through activation of a predominantly soluble guanylyl cyclase (sGC). In mammalian cells sGC exists as a heterodimer of α and β subunits. Currently, four subunits (α1, α2, β1, and β2) have been characterized. We used in situ hybridization wi...

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