Cardiovascular Risk Factors and Excess Adiposity Among Overweight Children and Adolescents: The Bogalusa Heart Study
Objective To explore the accuracy of various body mass index (BMI) cutpoints in identifying children who have excess adiposity (based on skinfold thicknesses), adverse levels of lipids, insulin, and blood pressures, and a high risk for severe adult obesity. Study design Cross-sectional (n = 10,099)...
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| Veröffentlicht in: | The Journal of pediatrics 2007, Vol.150 (1), p.12-17.e2 |
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| container_title | The Journal of pediatrics |
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| creator | Freedman, David S., PhD Mei, Zuguo, MD, PhD Srinivasan, Sathanur R., PhD Berenson, Gerald S., MD Dietz, William H., MD |
| description | Objective To explore the accuracy of various body mass index (BMI) cutpoints in identifying children who have excess adiposity (based on skinfold thicknesses), adverse levels of lipids, insulin, and blood pressures, and a high risk for severe adult obesity. Study design Cross-sectional (n = 10,099) and longitudinal (n = 2392) analyses were performed among subjects who participated in the Bogalusa Heart Study. Results Of children with a BMI ≥95th percentile (P) of the Centers for Disease Control (CDC) growth charts, 39% had at least two risk factors, 65% had excess adiposity, and 65% had an adult BMI of ≥35 kg/m2 . Of those with a BMI ≥99th P, 59% had at least two risk factors, 94% had excess adiposity, and 88% had an adult BMI of ≥35 kg/m2 . About 4% of children in the US now have a BMI ≥99th P. Conclusions The 99th P of BMI-for-age may be appropriate for identifying children who are at very high risk for biochemical abnormalities and severe adult obesity. More aggressive weight control strategies may be warranted for this subgroup. |
| doi_str_mv | 10.1016/j.jpeds.2006.08.042 |
| format | Article |
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Study design Cross-sectional (n = 10,099) and longitudinal (n = 2392) analyses were performed among subjects who participated in the Bogalusa Heart Study. Results Of children with a BMI ≥95th percentile (P) of the Centers for Disease Control (CDC) growth charts, 39% had at least two risk factors, 65% had excess adiposity, and 65% had an adult BMI of ≥35 kg/m2 . Of those with a BMI ≥99th P, 59% had at least two risk factors, 94% had excess adiposity, and 88% had an adult BMI of ≥35 kg/m2 . About 4% of children in the US now have a BMI ≥99th P. Conclusions The 99th P of BMI-for-age may be appropriate for identifying children who are at very high risk for biochemical abnormalities and severe adult obesity. More aggressive weight control strategies may be warranted for this subgroup.</description><identifier>ISSN: 0022-3476</identifier><identifier>EISSN: 1097-6833</identifier><identifier>DOI: 10.1016/j.jpeds.2006.08.042</identifier><identifier>PMID: 17188605</identifier><identifier>CODEN: JOPDAB</identifier><language>eng</language><publisher>New York, NY: Mosby, Inc</publisher><subject>Adolescent ; Adult ; Age Factors ; Atherosclerosis (general aspects, experimental research) ; Biological and medical sciences ; Blood and lymphatic vessels ; Body Mass Index ; Cardiology. Vascular system ; Cardiovascular Diseases - blood ; Cardiovascular Diseases - epidemiology ; Cardiovascular Diseases - etiology ; Child ; Child, Preschool ; Cholesterol, LDL - blood ; Coronary heart disease ; Cross-Sectional Studies ; Female ; Follow-Up Studies ; General aspects ; Heart ; Humans ; Louisiana - epidemiology ; Male ; Medical sciences ; Obesity - blood ; Obesity - complications ; Obesity - epidemiology ; Overweight ; Pediatrics ; Prevalence ; Risk Factors ; Sex Factors ; Triglycerides - blood</subject><ispartof>The Journal of pediatrics, 2007, Vol.150 (1), p.12-17.e2</ispartof><rights>Mosby, Inc.</rights><rights>2007 Mosby, Inc.</rights><rights>2008 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c508t-36380eb72f2a3b8eede52205a7a8d4d0cf4c6bab355005730887190c68f777b03</citedby><cites>FETCH-LOGICAL-c508t-36380eb72f2a3b8eede52205a7a8d4d0cf4c6bab355005730887190c68f777b03</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.jpeds.2006.08.042$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,777,781,3537,4010,27904,27905,27906,45976</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=19880476$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/17188605$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Freedman, David S., PhD</creatorcontrib><creatorcontrib>Mei, Zuguo, MD, PhD</creatorcontrib><creatorcontrib>Srinivasan, Sathanur R., PhD</creatorcontrib><creatorcontrib>Berenson, Gerald S., MD</creatorcontrib><creatorcontrib>Dietz, William H., MD</creatorcontrib><title>Cardiovascular Risk Factors and Excess Adiposity Among Overweight Children and Adolescents: The Bogalusa Heart Study</title><title>The Journal of pediatrics</title><addtitle>J Pediatr</addtitle><description>Objective To explore the accuracy of various body mass index (BMI) cutpoints in identifying children who have excess adiposity (based on skinfold thicknesses), adverse levels of lipids, insulin, and blood pressures, and a high risk for severe adult obesity. Study design Cross-sectional (n = 10,099) and longitudinal (n = 2392) analyses were performed among subjects who participated in the Bogalusa Heart Study. Results Of children with a BMI ≥95th percentile (P) of the Centers for Disease Control (CDC) growth charts, 39% had at least two risk factors, 65% had excess adiposity, and 65% had an adult BMI of ≥35 kg/m2 . Of those with a BMI ≥99th P, 59% had at least two risk factors, 94% had excess adiposity, and 88% had an adult BMI of ≥35 kg/m2 . About 4% of children in the US now have a BMI ≥99th P. Conclusions The 99th P of BMI-for-age may be appropriate for identifying children who are at very high risk for biochemical abnormalities and severe adult obesity. More aggressive weight control strategies may be warranted for this subgroup.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Age Factors</subject><subject>Atherosclerosis (general aspects, experimental research)</subject><subject>Biological and medical sciences</subject><subject>Blood and lymphatic vessels</subject><subject>Body Mass Index</subject><subject>Cardiology. Vascular system</subject><subject>Cardiovascular Diseases - blood</subject><subject>Cardiovascular Diseases - epidemiology</subject><subject>Cardiovascular Diseases - etiology</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Cholesterol, LDL - blood</subject><subject>Coronary heart disease</subject><subject>Cross-Sectional Studies</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>General aspects</subject><subject>Heart</subject><subject>Humans</subject><subject>Louisiana - epidemiology</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Obesity - blood</subject><subject>Obesity - complications</subject><subject>Obesity - epidemiology</subject><subject>Overweight</subject><subject>Pediatrics</subject><subject>Prevalence</subject><subject>Risk Factors</subject><subject>Sex Factors</subject><subject>Triglycerides - blood</subject><issn>0022-3476</issn><issn>1097-6833</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2007</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFktFu0zAUhiMEYt3gCZCQb-Au4SROYhcJpFJtDGnSJDauLcc-aZ2lcfFJCn37uWulSdxw5ZvvP_71nZMk73LIcsjrT13WbdFSVgDUGcgMyuJFMsthLtJacv4ymQEURcpLUZ8l50QdAMxLgNfJWS5yKWuoZsm41ME6v9Nkpl4H9tPRA7vSZvSBmB4su_xrkIgtrNt6cuOeLTZ-WLHbHYY_6FbrkS3XrrcBhyd8YX2PZHAY6TO7XyP75le6n0iza9RhZHfjZPdvklet7gnfnt6L5NfV5f3yOr25_f5jubhJTQVyTHnNJWAjirbQvJGIFquigEoLLW1pwbSlqRvd8KoCqAQHKUU-B1PLVgjRAL9IPh7nboP_PSGNauNit77XA_qJVNQkKshFBPkRNMETBWzVNriNDnuVgzrIVp16kq0OshVIFWXH1PvT-KnZoH3OnOxG4MMJiHp13wY9GEfP3FxKiNuJ3Jcjh1HGzmFQZBwOBq0LaEZlvftPka__5E3vBhe_fMA9UuenMETPKldUKFB3h7s4nAXUADK25Y83FbNo</recordid><startdate>2007</startdate><enddate>2007</enddate><creator>Freedman, David S., PhD</creator><creator>Mei, Zuguo, MD, PhD</creator><creator>Srinivasan, Sathanur R., PhD</creator><creator>Berenson, Gerald S., MD</creator><creator>Dietz, William H., MD</creator><general>Mosby, Inc</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>2007</creationdate><title>Cardiovascular Risk Factors and Excess Adiposity Among Overweight Children and Adolescents: The Bogalusa Heart Study</title><author>Freedman, David S., PhD ; Mei, Zuguo, MD, PhD ; Srinivasan, Sathanur R., PhD ; Berenson, Gerald S., MD ; Dietz, William H., MD</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c508t-36380eb72f2a3b8eede52205a7a8d4d0cf4c6bab355005730887190c68f777b03</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2007</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Age Factors</topic><topic>Atherosclerosis (general aspects, experimental research)</topic><topic>Biological and medical sciences</topic><topic>Blood and lymphatic vessels</topic><topic>Body Mass Index</topic><topic>Cardiology. Vascular system</topic><topic>Cardiovascular Diseases - blood</topic><topic>Cardiovascular Diseases - epidemiology</topic><topic>Cardiovascular Diseases - etiology</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>Cholesterol, LDL - blood</topic><topic>Coronary heart disease</topic><topic>Cross-Sectional Studies</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>General aspects</topic><topic>Heart</topic><topic>Humans</topic><topic>Louisiana - epidemiology</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Obesity - blood</topic><topic>Obesity - complications</topic><topic>Obesity - epidemiology</topic><topic>Overweight</topic><topic>Pediatrics</topic><topic>Prevalence</topic><topic>Risk Factors</topic><topic>Sex Factors</topic><topic>Triglycerides - blood</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Freedman, David S., PhD</creatorcontrib><creatorcontrib>Mei, Zuguo, MD, PhD</creatorcontrib><creatorcontrib>Srinivasan, Sathanur R., PhD</creatorcontrib><creatorcontrib>Berenson, Gerald S., MD</creatorcontrib><creatorcontrib>Dietz, William H., MD</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The Journal of pediatrics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Freedman, David S., PhD</au><au>Mei, Zuguo, MD, PhD</au><au>Srinivasan, Sathanur R., PhD</au><au>Berenson, Gerald S., MD</au><au>Dietz, William H., MD</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Cardiovascular Risk Factors and Excess Adiposity Among Overweight Children and Adolescents: The Bogalusa Heart Study</atitle><jtitle>The Journal of pediatrics</jtitle><addtitle>J Pediatr</addtitle><date>2007</date><risdate>2007</risdate><volume>150</volume><issue>1</issue><spage>12</spage><epage>17.e2</epage><pages>12-17.e2</pages><issn>0022-3476</issn><eissn>1097-6833</eissn><coden>JOPDAB</coden><abstract>Objective To explore the accuracy of various body mass index (BMI) cutpoints in identifying children who have excess adiposity (based on skinfold thicknesses), adverse levels of lipids, insulin, and blood pressures, and a high risk for severe adult obesity. Study design Cross-sectional (n = 10,099) and longitudinal (n = 2392) analyses were performed among subjects who participated in the Bogalusa Heart Study. Results Of children with a BMI ≥95th percentile (P) of the Centers for Disease Control (CDC) growth charts, 39% had at least two risk factors, 65% had excess adiposity, and 65% had an adult BMI of ≥35 kg/m2 . Of those with a BMI ≥99th P, 59% had at least two risk factors, 94% had excess adiposity, and 88% had an adult BMI of ≥35 kg/m2 . About 4% of children in the US now have a BMI ≥99th P. Conclusions The 99th P of BMI-for-age may be appropriate for identifying children who are at very high risk for biochemical abnormalities and severe adult obesity. More aggressive weight control strategies may be warranted for this subgroup.</abstract><cop>New York, NY</cop><pub>Mosby, Inc</pub><pmid>17188605</pmid><doi>10.1016/j.jpeds.2006.08.042</doi><tpages>6</tpages></addata></record> |
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| subjects | Adolescent Adult Age Factors Atherosclerosis (general aspects, experimental research) Biological and medical sciences Blood and lymphatic vessels Body Mass Index Cardiology. Vascular system Cardiovascular Diseases - blood Cardiovascular Diseases - epidemiology Cardiovascular Diseases - etiology Child Child, Preschool Cholesterol, LDL - blood Coronary heart disease Cross-Sectional Studies Female Follow-Up Studies General aspects Heart Humans Louisiana - epidemiology Male Medical sciences Obesity - blood Obesity - complications Obesity - epidemiology Overweight Pediatrics Prevalence Risk Factors Sex Factors Triglycerides - blood |
| title | Cardiovascular Risk Factors and Excess Adiposity Among Overweight Children and Adolescents: The Bogalusa Heart Study |
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