Crystal structure of human TMDP, a testis-specific dual specificity protein phosphatase: Implications for substrate specificity

The testis‐ and skeletal‐muscle‐specific dual‐specificity phosphatase (TMDP) is a member of the dual‐specificity phosphatase (DSP) subgroup of protein tyrosine phosphatases. TMDP has similar activities toward both tyrosine and threonine phosphorylated substrates, and is supposed to be involved in sp...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Proteins, structure, function, and bioinformatics structure, function, and bioinformatics, 2007-01, Vol.66 (1), p.239-245
Hauptverfasser:	Kim, Seung Jun, Jeong, Dae-Gwin, Yoon, Tae-Sung, Son, Jeong-Hee, Cho, Somi Kim, Ryu, Seong Eon, Kim, Jae-Hoon
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Binding Sites crystal structure Crystallography, X-Ray dual-specificity phosphatase Dual-Specificity Phosphatases Helix-Loop-Helix Motifs Humans Male Models, Molecular Molecular Sequence Data Muscle, Skeletal - enzymology Phosphoprotein Phosphatases - chemistry Phosphoprotein Phosphatases - metabolism Protein Tyrosine Phosphatases - chemistry Protein Tyrosine Phosphatases - metabolism Sequence Alignment Substrate Specificity Testis - enzymology Threonine - metabolism TMDP Tyrosine - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!