MTHFR C677T and A1298C gene polymorphisms and hyperhomocysteinemia as risk factors of diabetic nephropathy in type 2 diabetes patients

Abstract Point mutations in methylenetetrahydrofolate reductase (MTHFR) and hyperhomocysteinemia were implicated in the pathogenesis of diabetic nephropathy (DN) in many ethnic groups. This study addressed the association of C677T and A1298C single nucleotide polymorphisms (SNPs) of MTHFR gene with...

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Veröffentlicht in:	Diabetes research and clinical practice 2007-01, Vol.75 (1), p.99-106
Hauptverfasser:	Mtiraoui, Nabil, Ezzidi, Intissar, Chaieb, Molka, Marmouche, Hela, Aouni, Zied, Chaieb, Arbi, Mahjoub, Touhami, Vaxillaire, Martine, Almawi, Wassim Y
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Diabetes Diabetes Mellitus, Type 2 - complications Diabetes Mellitus, Type 2 - epidemiology Diabetes Mellitus, Type 2 - genetics Diabetic Nephropathies - epidemiology Diabetic Nephropathies - genetics Endocrinology & Metabolism Female Genotype Homocysteine Homocysteine - blood Humans Hyperhomocysteinemia - complications Male Methylenetetrahydrofolate Reductase (NADPH2) - genetics Middle Aged MTHFR Nephropathy Polymorphism, Single Nucleotide Risk Factors Tunisia - epidemiology
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