Gamma glutamyl transpeptidase is a dynamic indicator of endothelial response to stroke

Gamma glutamyl transpeptidase (γGT) is enriched at the apical surface of the cerebral capillaries that constitute the blood–brain barrier (BBB). This study tested the effects of hypoxia and inflammation on γGT activity in mice after stroke induced by transient cerebral artery occlusion (tMCAO) and i...

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Veröffentlicht in:	Experimental neurology 2007, Vol.203 (1), p.116-122
Hauptverfasser:	Yu, Chuanhui, Kastin, Abba J., Ding, Yuemin, Pan, Weihong
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Triphosphate - metabolism Animals Biological and medical sciences Blood-Brain Barrier - enzymology Blood-Brain Barrier - physiopathology Blood. Blood coagulation. Reticuloendothelial system Blood–brain barrier Capillaries - enzymology Capillaries - physiopathology Cells, Cultured Cerebral Arteries - enzymology Cerebral Arteries - physiopathology Cerebrovascular Circulation - physiology Disease Models, Animal Encephalitis - enzymology Encephalitis - physiopathology Endothelium, Vascular - enzymology Endothelium, Vascular - physiopathology gamma-Glutamyltransferase - metabolism Hypoxia Hypoxia, Brain - enzymology Hypoxia, Brain - physiopathology Infarction, Middle Cerebral Artery - enzymology Infarction, Middle Cerebral Artery - physiopathology Inflammation Inflammation Mediators - pharmacology Ischemia Male Medical sciences Mice Mice, Inbred C57BL Neurology Pharmacology. Drug treatments Stroke Stroke - enzymology Stroke - physiopathology Time Factors Vascular diseases and vascular malformations of the nervous system γGT
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