A rat model of cardiopulmonary bypass with cardioplegic arrest and hemodynamic assessment by conductance catheter technique

Cardiopulmonary bypass (CPB) is known to induce systemic inflammation and cardiac dysfunction associated with a significant morbidity. Aim of the study was to develop an in vivo model of rat CPB with hypothermic cardiac arrest and the use of cardioplegia. The CPB circuit consisted of a venous reserv...

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Veröffentlicht in:	Basic research in cardiology 2007-11, Vol.102 (6), p.508-517
Hauptverfasser:	Günzinger, Ralf, Wildhirt, Stephen M, Schad, Hubert, Heimisch, Werner, Gurdan, Manuela, Mendler, Nikolaus, Grammer, Joachim, Lange, Rüdiger, Bauernschmitt, Robert
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Blood Pressure - physiology Cardiac Catheterization - methods Cardiopulmonary Bypass - methods Heart - physiopathology Heart Arrest, Induced - methods Heart Rate - physiology Heart Ventricles - physiopathology Hypothermia, Induced Interleukin-6 - metabolism Male Models, Animal Myocardium - metabolism Rats Rats, Wistar RNA, Messenger - metabolism Surgical Instruments Tumor Necrosis Factor-alpha - metabolism
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