TH2 and TH1 lung inflammation induced by airway allergen sensitization with low and high doses of double-stranded RNA

Although respiratory viral infections in early childhood can enhance the development of airway allergen sensitization, the exact mechanisms of the effects of viral infections on the adaptive immune response to inhaled allergens are controversial. We sought to evaluate the effects of double-stranded...

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Veröffentlicht in:	Journal of allergy and clinical immunology 2007-10, Vol.120 (4), p.803-812
Hauptverfasser:	SEONG GYU JEON, OH, Sun-Young, YONG SONG GHO, ZHOU ZHU, KIM, You-Young, KIM, Yoon-Keun, PARK, Hye-Kyung, KIM, You-Sun, SHIM, Eun-Jin, LEE, Hyun-Seung, OH, Min-Hee, BANG, Boram, CHUN, Eun-Young, KIM, Sang-Heon
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergens - immunology Allergies Animals Asthma - etiology Biological and medical sciences Bronchial Hyperreactivity - etiology Fundamental and applied biological sciences. Psychology Fundamental immunology Immune system Immunopathology Interferon-gamma - physiology Interleukin-13 - physiology Interleukin-4 - physiology Lymphocytes Medical sciences Mice Mice, Inbred BALB C Mice, Inbred C57BL Ovalbumin - immunology Poly I-C - administration & dosage Proteins RNA, Double-Stranded - administration & dosage Rodents Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis Signal Transduction STAT6 Transcription Factor - physiology Studies Th1 Cells - immunology Th2 Cells - immunology Toll-Like Receptor 3 - physiology Viral infections
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