Molecular definition of chromosome arm 5q deletion end points and detection of hidden aberrations in patients with myelodysplastic syndromes and isolated del(5q) using oligonucleotide array CGH

Isolated deletions of the long arm of chromosome 5, del(5q), are observed in 10% of myelodysplastic syndromes (MDS) and are associated with a more favorable prognosis, although the clinical course varies considerably. If one or more additional chromosomal aberrations are present, this correlates wit...

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Veröffentlicht in:	Genes chromosomes & cancer 2007-12, Vol.46 (12), p.1119-1128
Hauptverfasser:	Evers, Christina, Beier, Manfred, Poelitz, Anne, Hildebrandt, Barbara, Servan, Kati, Drechsler, Matthias, Germing, Ulrich, Royer, Hans-Dieter, Royer-Pokora, Brigitte
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Bone Marrow Cells - metabolism Chromosome Aberrations Chromosome Deletion Chromosomes, Human, Pair 5 Female Genome, Human Humans In Situ Hybridization, Fluorescence Male Middle Aged Myelodysplastic Syndromes - genetics Oligonucleotide Array Sequence Analysis - methods
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