Chronobiology of hemostasis and inferences for the chronotherapy of coagulation disorders and thrombosis prevention

The hemostatic system in its multiple components displays an intricate organization in time which is characterized by circadian (∼ 24-hour), circaseptan (∼ 7-day), menstrual (∼ monthly), and circannual (∼ yearly) bioperiodicities. The interaction of the rhythms of the variables participating in hemo...

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Veröffentlicht in:	Advanced drug delivery reviews 2007-08, Vol.59 (9), p.966-984
1. Verfasser:	Haus, Erhard
Format:	Artikel
Sprache:	eng
Schlagworte:	Autonomic Nervous System - physiology Blood Coagulation Blood Coagulation Disorders - drug therapy Chronobiology Phenomena - physiology Chronopharmacology of anticoagulants Circadian Rhythm - physiology Female Fibrinolysis Hemostasis - physiology Heparin - therapeutic use Human time organization Humans Menstrual Cycle Platelet Aggregation Inhibitors - therapeutic use Platelet Count Rhythms in blood coagulation Thrombocytes Thrombolytic Therapy Thrombosis - prevention & control Vitamin K - antagonists & inhibitors
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