Uptake of 4-borono-2-[18F]fluoro-L-phenylalanine in sporadic and neurofibromatosis 2-related schwannoma and meningioma studied with PET

Meningiomas and schwannomas associated with neurofibromatosis 2 (NF2) are difficult to control by microsurgery and stereotactic radiotherapy alone. Boron neutron capture therapy (BNCT) is a chemically targeted form of radiotherapy requiring increased concentration of boron-10 in tumour tissue. PET w...

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Veröffentlicht in:	European journal of nuclear medicine and molecular imaging 2007-01, Vol.34 (1), p.87-94
Hauptverfasser:	Havu-Aurén, Katja, Kiiski, Johanna, Lehtiö, Kaisa, Eskola, Olli, Kulvik, Martti, Vuorinen, Ville, Oikonen, Vesa, Vähätalo, Jyrki, Jääskeläinen, Juha, Minn, Heikki
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Boron Compounds - pharmacokinetics Boron Compounds - therapeutic use Boron Neutron Capture Therapy - methods Brain Neoplasms - diagnostic imaging Brain Neoplasms - etiology Brain Neoplasms - metabolism Brain Neoplasms - radiotherapy Cancer Chemotherapy Female Humans Male Medical disorders Meningeal Neoplasms - diagnostic imaging Meningeal Neoplasms - etiology Meningeal Neoplasms - metabolism Meningeal Neoplasms - radiotherapy Meningioma - diagnostic imaging Meningioma - etiology Meningioma - metabolism Meningioma - radiotherapy Middle Aged Neurilemmoma - diagnostic imaging Neurilemmoma - etiology Neurilemmoma - metabolism Neurilemmoma - radiotherapy Neurofibromatoses - complications Neurofibromatoses - diagnostic imaging Neurofibromatoses - metabolism Neurofibromatoses - radiotherapy Phenylalanine - analogs & derivatives Phenylalanine - pharmacokinetics Phenylalanine - therapeutic use Positron-Emission Tomography - methods Radiation therapy Radiopharmaceuticals - pharmacokinetics Radiopharmaceuticals - therapeutic use Tumors
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