Vitamin B12 status of Thai women with neoplasia of the cervix uteri
The vitamin B12 statuses of Thai women with high- and low-grade cervical dysplasia were studied and compared with women with normal cytological smears. Serum vitamin B12 and vitamin B12 intakes were assessed, as well as demographic characteristics, sexual behavior, reproductive and menstrual history...
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| Veröffentlicht in: | Southeast Asian journal of tropical medicine and public health 2006, Vol.37 Suppl 3, p.178-183 |
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| container_title | Southeast Asian journal of tropical medicine and public health |
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| creator | Kwanbunjan, Karunee Saengkar, Phimonsri Cheeramakara, Cheeraratana Tangjitgamol, Siriwan Chitcharoenrung, Kulrat |
| description | The vitamin B12 statuses of Thai women with high- and low-grade cervical dysplasia were studied and compared with women with normal cytological smears. Serum vitamin B12 and vitamin B12 intakes were assessed, as well as demographic characteristics, sexual behavior, reproductive and menstrual history, exogenous hormone use, personal and familial medical history, smoking habit, and other risk factors. The presence or absence of genital HPV DNA was determined by polymerase chain reaction (PCR). Serum vitamin B12 levels in women with normal cytological smears were significantly higher than those with both high- and low-grade cervical dysplasia (p |
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Serum vitamin B12 and vitamin B12 intakes were assessed, as well as demographic characteristics, sexual behavior, reproductive and menstrual history, exogenous hormone use, personal and familial medical history, smoking habit, and other risk factors. The presence or absence of genital HPV DNA was determined by polymerase chain reaction (PCR). Serum vitamin B12 levels in women with normal cytological smears were significantly higher than those with both high- and low-grade cervical dysplasia (p<0.001). Low vitamin B12 serum levels were significantly statistically associated with increased low-grade (OR = 4.08; 95% CI = 1.41-11.79; p < 0.05) and increased high-grade cervical dysplasia risk (OR = 3.53; 95% CI = 1.24-10.04; p< 0.05) for the highest vs lowest quartiles of serum vitamin B12. This study indicated a relationship between low vitamin B12 status and increased risk of cervical cancer.</description><identifier>ISSN: 0125-1562</identifier><identifier>PMID: 17547077</identifier><language>eng</language><publisher>Thailand</publisher><subject>Adolescent ; Adult ; Aged ; Analysis of Variance ; Case-Control Studies ; Cervix Uteri ; Chi-Square Distribution ; Female ; Humans ; Middle Aged ; Odds Ratio ; Risk Factors ; Uterine Cervical Neoplasms - blood ; Vitamin B 12 - blood</subject><ispartof>Southeast Asian journal of tropical medicine and public health, 2006, Vol.37 Suppl 3, p.178-183</ispartof><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,4022</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/17547077$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kwanbunjan, Karunee</creatorcontrib><creatorcontrib>Saengkar, Phimonsri</creatorcontrib><creatorcontrib>Cheeramakara, Cheeraratana</creatorcontrib><creatorcontrib>Tangjitgamol, Siriwan</creatorcontrib><creatorcontrib>Chitcharoenrung, Kulrat</creatorcontrib><title>Vitamin B12 status of Thai women with neoplasia of the cervix uteri</title><title>Southeast Asian journal of tropical medicine and public health</title><addtitle>Southeast Asian J Trop Med Public Health</addtitle><description>The vitamin B12 statuses of Thai women with high- and low-grade cervical dysplasia were studied and compared with women with normal cytological smears. 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This study indicated a relationship between low vitamin B12 status and increased risk of cervical cancer.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Analysis of Variance</subject><subject>Case-Control Studies</subject><subject>Cervix Uteri</subject><subject>Chi-Square Distribution</subject><subject>Female</subject><subject>Humans</subject><subject>Middle Aged</subject><subject>Odds Ratio</subject><subject>Risk Factors</subject><subject>Uterine Cervical Neoplasms - blood</subject><subject>Vitamin B 12 - blood</subject><issn>0125-1562</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2006</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo1T8lOwzAU9AFES-AXkE_cIvk970eIWCpV4lK4Rm7qKEbZiB0Kf08Q5TQjzWiWM7JmgDIHqXBFLmN8Z0wwsOaCrEBLoZnWa1K8heS60NN7QBqTS3OkQ013jQv0OHS-p8eQGtr7YWxdDO5XTI2nlZ8-wxedk5_CFTmvXRv99Qkz8vr4sCue8-3L06a42-YjoEi5VbWTEjmzQkkNduEVd17VxlQSLaLyiMIoedCa7cHwGjRHBVyDEQiCZ-T2L3echo_Zx1R2IVa-bd0yb46lMlxaXBoycnMyzvvOH8pxCp2bvsv_2_wH-ZpPbg</recordid><startdate>2006</startdate><enddate>2006</enddate><creator>Kwanbunjan, Karunee</creator><creator>Saengkar, Phimonsri</creator><creator>Cheeramakara, Cheeraratana</creator><creator>Tangjitgamol, Siriwan</creator><creator>Chitcharoenrung, Kulrat</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>2006</creationdate><title>Vitamin B12 status of Thai women with neoplasia of the cervix uteri</title><author>Kwanbunjan, Karunee ; Saengkar, Phimonsri ; Cheeramakara, Cheeraratana ; Tangjitgamol, Siriwan ; Chitcharoenrung, Kulrat</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p124t-96fa552309465719552c3ae6f88c529226e224865d770b183f173261371842143</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2006</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Aged</topic><topic>Analysis of Variance</topic><topic>Case-Control Studies</topic><topic>Cervix Uteri</topic><topic>Chi-Square Distribution</topic><topic>Female</topic><topic>Humans</topic><topic>Middle Aged</topic><topic>Odds Ratio</topic><topic>Risk Factors</topic><topic>Uterine Cervical Neoplasms - blood</topic><topic>Vitamin B 12 - blood</topic><toplevel>online_resources</toplevel><creatorcontrib>Kwanbunjan, Karunee</creatorcontrib><creatorcontrib>Saengkar, Phimonsri</creatorcontrib><creatorcontrib>Cheeramakara, Cheeraratana</creatorcontrib><creatorcontrib>Tangjitgamol, Siriwan</creatorcontrib><creatorcontrib>Chitcharoenrung, Kulrat</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Southeast Asian journal of tropical medicine and public health</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kwanbunjan, Karunee</au><au>Saengkar, Phimonsri</au><au>Cheeramakara, Cheeraratana</au><au>Tangjitgamol, Siriwan</au><au>Chitcharoenrung, Kulrat</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Vitamin B12 status of Thai women with neoplasia of the cervix uteri</atitle><jtitle>Southeast Asian journal of tropical medicine and public health</jtitle><addtitle>Southeast Asian J Trop Med Public Health</addtitle><date>2006</date><risdate>2006</risdate><volume>37 Suppl 3</volume><spage>178</spage><epage>183</epage><pages>178-183</pages><issn>0125-1562</issn><abstract>The vitamin B12 statuses of Thai women with high- and low-grade cervical dysplasia were studied and compared with women with normal cytological smears. 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| ispartof | Southeast Asian journal of tropical medicine and public health, 2006, Vol.37 Suppl 3, p.178-183 |
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| language | eng |
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| source | MEDLINE; EZB-FREE-00999 freely available EZB journals |
| subjects | Adolescent Adult Aged Analysis of Variance Case-Control Studies Cervix Uteri Chi-Square Distribution Female Humans Middle Aged Odds Ratio Risk Factors Uterine Cervical Neoplasms - blood Vitamin B 12 - blood |
| title | Vitamin B12 status of Thai women with neoplasia of the cervix uteri |
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