Recommendations for the Management of Herpes Zoster

The objective of this article is to provide evidence-based recommendations for the management of patients with herpes zoster (HZ) that take into account clinical efficacy, adverse effects, impact on quality of life, and costs of treatment. Systematic literature reviews, published randomized clinical...

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Veröffentlicht in:Clinical infectious diseases 2007-01, Vol.44 (Supplement-1), p.S1-S26
Hauptverfasser: Dworkin, Robert H., Johnson, Robert W., Breuer, Judith, Gnann, John W., Levin, Myron J., Backonja, Miroslav, Betts, Robert F., Gershon, Anne A., Haanpää, Maija L., McKendrick, Michael W., Nurmikko, Turo J., Oaklander, Anne Louise, Oxman, Michael N., Langston, Deborah Pavan, Petersen, Karin L., Rowbotham, Michael C., Schmader, Kenneth E., Stacey, Brett R., Tyring, Stephen K., Wijck, Albert J. M. van, Wallace, Mark S., Wassilew, Sawko W., Whitley, Richard J.
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container_end_page S26
container_issue Supplement-1
container_start_page S1
container_title Clinical infectious diseases
container_volume 44
creator Dworkin, Robert H.
Johnson, Robert W.
Breuer, Judith
Gnann, John W.
Levin, Myron J.
Backonja, Miroslav
Betts, Robert F.
Gershon, Anne A.
Haanpää, Maija L.
McKendrick, Michael W.
Nurmikko, Turo J.
Oaklander, Anne Louise
Oxman, Michael N.
Langston, Deborah Pavan
Petersen, Karin L.
Rowbotham, Michael C.
Schmader, Kenneth E.
Stacey, Brett R.
Tyring, Stephen K.
Wijck, Albert J. M. van
Wallace, Mark S.
Wassilew, Sawko W.
Whitley, Richard J.
description The objective of this article is to provide evidence-based recommendations for the management of patients with herpes zoster (HZ) that take into account clinical efficacy, adverse effects, impact on quality of life, and costs of treatment. Systematic literature reviews, published randomized clinical trials, existing guidelines, and the authors' clinical and research experience relevant to the management of patients with HZ were reviewed at a consensus meeting. The results of controlled trials and the clinical experience of the authors support the use of acyclovir, brivudin (where available), famciclovir, and valacyclovir as first-line antiviral therapy for the treatment of patients with HZ. Specific recommendations for the use of these medications are provided. In addition, suggestions are made for treatments that, when used in combination with antiviral therapy, may further reduce pain and other complications of HZ.
doi_str_mv 10.1086/510206
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M. van</creatorcontrib><creatorcontrib>Wallace, Mark S.</creatorcontrib><creatorcontrib>Wassilew, Sawko W.</creatorcontrib><creatorcontrib>Whitley, Richard J.</creatorcontrib><title>Recommendations for the Management of Herpes Zoster</title><title>Clinical infectious diseases</title><addtitle>Clinical Infectious Diseases</addtitle><description>The objective of this article is to provide evidence-based recommendations for the management of patients with herpes zoster (HZ) that take into account clinical efficacy, adverse effects, impact on quality of life, and costs of treatment. Systematic literature reviews, published randomized clinical trials, existing guidelines, and the authors' clinical and research experience relevant to the management of patients with HZ were reviewed at a consensus meeting. 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Antiparasitic agents</subject><subject>Antiviral agents</subject><subject>Antiviral Agents - therapeutic use</subject><subject>Antivirals</subject><subject>Biological and medical sciences</subject><subject>Bromodeoxyuridine - analogs &amp; derivatives</subject><subject>Bromodeoxyuridine - therapeutic use</subject><subject>Chickenpox</subject><subject>Exanthema</subject><subject>Herpes zoster</subject><subject>Herpes Zoster - complications</subject><subject>Herpes Zoster - drug therapy</subject><subject>Herpes Zoster - epidemiology</subject><subject>Herpes Zoster - physiopathology</subject><subject>Herpesvirus 3, Human - pathogenicity</subject><subject>Human herpesvirus 3</subject><subject>Human viral diseases</subject><subject>Humans</subject><subject>Immunocompetence</subject><subject>Immunocompromised Host</subject><subject>Infections</subject><subject>Infectious diseases</subject><subject>Medical sciences</subject><subject>Pain</subject><subject>Pharmacology. 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Drug treatments</topic><topic>Postherpetic neuralgia</topic><topic>Valine - analogs &amp; derivatives</topic><topic>Valine - therapeutic use</topic><topic>Varicella zoster encephalitis</topic><topic>Viral diseases</topic><topic>Viral diseases with cutaneous or mucosal lesions and viral diseases of the eye</topic><topic>Viruses</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Dworkin, Robert H.</creatorcontrib><creatorcontrib>Johnson, Robert W.</creatorcontrib><creatorcontrib>Breuer, Judith</creatorcontrib><creatorcontrib>Gnann, John W.</creatorcontrib><creatorcontrib>Levin, Myron J.</creatorcontrib><creatorcontrib>Backonja, Miroslav</creatorcontrib><creatorcontrib>Betts, Robert F.</creatorcontrib><creatorcontrib>Gershon, Anne A.</creatorcontrib><creatorcontrib>Haanpää, Maija L.</creatorcontrib><creatorcontrib>McKendrick, Michael W.</creatorcontrib><creatorcontrib>Nurmikko, Turo J.</creatorcontrib><creatorcontrib>Oaklander, Anne Louise</creatorcontrib><creatorcontrib>Oxman, Michael N.</creatorcontrib><creatorcontrib>Langston, Deborah Pavan</creatorcontrib><creatorcontrib>Petersen, Karin L.</creatorcontrib><creatorcontrib>Rowbotham, Michael C.</creatorcontrib><creatorcontrib>Schmader, Kenneth E.</creatorcontrib><creatorcontrib>Stacey, Brett R.</creatorcontrib><creatorcontrib>Tyring, Stephen K.</creatorcontrib><creatorcontrib>Wijck, Albert J. 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Systematic literature reviews, published randomized clinical trials, existing guidelines, and the authors' clinical and research experience relevant to the management of patients with HZ were reviewed at a consensus meeting. The results of controlled trials and the clinical experience of the authors support the use of acyclovir, brivudin (where available), famciclovir, and valacyclovir as first-line antiviral therapy for the treatment of patients with HZ. Specific recommendations for the use of these medications are provided. In addition, suggestions are made for treatments that, when used in combination with antiviral therapy, may further reduce pain and other complications of HZ.</abstract><cop>Chicago, IL</cop><pub>The University of Chicago Press</pub><pmid>17143845</pmid><doi>10.1086/510206</doi><oa>free_for_read</oa></addata></record>
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source MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Jstor Complete Legacy; Oxford University Press Journals All Titles (1996-Current)
subjects 2-Aminopurine - analogs & derivatives
2-Aminopurine - therapeutic use
Acyclovir - analogs & derivatives
Acyclovir - therapeutic use
Analgesics - therapeutic use
Anti-Inflammatory Agents - therapeutic use
Antibiotics. Antiinfectious agents. Antiparasitic agents
Antiviral agents
Antiviral Agents - therapeutic use
Antivirals
Biological and medical sciences
Bromodeoxyuridine - analogs & derivatives
Bromodeoxyuridine - therapeutic use
Chickenpox
Exanthema
Herpes zoster
Herpes Zoster - complications
Herpes Zoster - drug therapy
Herpes Zoster - epidemiology
Herpes Zoster - physiopathology
Herpesvirus 3, Human - pathogenicity
Human herpesvirus 3
Human viral diseases
Humans
Immunocompetence
Immunocompromised Host
Infections
Infectious diseases
Medical sciences
Pain
Pharmacology. Drug treatments
Postherpetic neuralgia
Valine - analogs & derivatives
Valine - therapeutic use
Varicella zoster encephalitis
Viral diseases
Viral diseases with cutaneous or mucosal lesions and viral diseases of the eye
Viruses
title Recommendations for the Management of Herpes Zoster
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