Reduced Expression of Focal Adhesion Kinase in Intrahepatic Cholangiocarcinoma Is Associated with Poor Tumor Differentiation

Objective: Focal adhesion kinase (FAK) expression has been linked to tumor cell invasion and metastasis, but its role in intrahepatic cholangiocarcinoma (ICC) has not been addressed. The goal of this study was to investigate FAK expression in ICC and to assess whether its expression is correlated wi...

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Veröffentlicht in:	Oncology 2006-01, Vol.71 (5-6), p.417-422
Hauptverfasser:	Ohta, Ryuji, Yamashita, Yo-ichi, Taketomi, Akinobu, Kitagawa, Dai, Kuroda, Yosuke, Itoh, Shinji, Aishima, Shin-ichi, Maehara, Yoshihiko
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Biological and medical sciences Biomarkers, Tumor - metabolism Cell Differentiation Cellular biology Cholangiocarcinoma - diagnosis Cholangiocarcinoma - metabolism Cholangiocarcinoma - pathology Clinical outcomes Disease-Free Survival Female Focal Adhesion Protein-Tyrosine Kinases - metabolism Gastroenterology. Liver. Pancreas. Abdomen Humans Kinases Laboratory/Clinical Translational Research Liver Neoplasms - diagnosis Liver Neoplasms - metabolism Liver Neoplasms - pathology Liver. Biliary tract. Portal circulation. Exocrine pancreas Male Medical prognosis Medical research Medical sciences Middle Aged Oncology Prognosis Survival Rate Tumors
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