Autophagosome formation: core machinery and adaptations

Eukaryotic cells employ autophagy to degrade damaged or obsolete organelles and proteins. Central to this process is the formation of autophagosomes, double-membrane vesicles responsible for delivering cytoplasmic material to lysosomes. In the past decade many autophagy-related genes, ATG, have been...

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Veröffentlicht in:	Nature cell biology 2007-10, Vol.9 (10), p.1102-1109
Hauptverfasser:	Xie, Zhiping, Klionsky, Daniel J
Format:	Artikel
Sprache:	eng
Schlagworte:	Autophagy Biomedical and Life Sciences Cancer Research Cell Biology Cell physiology Cytoplasm Developmental Biology Genes Kinases Life Sciences Lysosomes - metabolism Models, Biological Phagocytosis Phagosomes - metabolism Physiological aspects Physiology Protein Transport Proteins review-article Saccharomyces cerevisiae Proteins - metabolism Signal Transduction Stem Cells Yeast
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