Interplay between cystic fibrosis transmembrane regulator and gap junction channels made of connexins 45, 40, 32 and 50 expressed in oocytes

The cystic fibrosis transmembrane regulator (CFTR) is a Cl(-) channel known to influence other channels, including connexin (Cx) channels. To study the functional interaction between CFTR and gap junction channels, we coexpressed in Xenopus oocytes CFTR and either Cx45, Cx40, Cx32 or Cx50 and monito...

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Veröffentlicht in:	The Journal of membrane biology 2006-11, Vol.214 (1), p.1-8
Hauptverfasser:	Kotsias, Basilio A, Salim, Mohammad, Peracchia, Lillian L, Peracchia, Camillo
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cellular biology Chlorides - metabolism Colforsin - pharmacology Connexins - genetics Connexins - metabolism Cystic fibrosis Cystic Fibrosis Transmembrane Conductance Regulator - genetics Cystic Fibrosis Transmembrane Conductance Regulator - metabolism Cytoskeletal Proteins - genetics Cytoskeletal Proteins - metabolism Eye Proteins - genetics Eye Proteins - metabolism Female Gap Junction alpha-5 Protein Gap Junction beta-1 Protein Gap Junctions - genetics Gap Junctions - metabolism Gene Expression Humans Ion Channel Gating - drug effects Ion Channel Gating - physiology Membrane Potentials - drug effects Membrane Potentials - physiology Membranes Mice Oocytes - cytology Protein Structure, Tertiary - genetics Proteins Rats Recombinant Proteins Xenopus laevis
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