Comparative effects of melatonin and vitamin E in restoring aortic relaxation in pancreatectomized rats

In a previous study we reported the efficacy of melatonin to restore the decreased relaxation response to acetylcholine (ACh) or to sodium nitroprusside (SNP) in aortic rings of rats turned hyperglycemic by subtotal pancreatectomy. The effect was amplified by pre-incubation in a high (44 mmol/l) glu...

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Veröffentlicht in:	Journal of physiology and biochemistry 2006-09, Vol.62 (3), p.207-212
Hauptverfasser:	Reyes-Toso, C F, Linares, L M, Albornoz, L E, Obaya-Naredo, D, Wallinger, M L, Ricci, C R, Cardinali, D P
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylcholine - pharmacology Animals Antioxidants - pharmacology Aorta, Thoracic - drug effects Aorta, Thoracic - physiology Endothelium, Vascular - drug effects Endothelium, Vascular - physiology Glucose - pharmacology Male Melatonin - pharmacology Nitroprusside - pharmacology Pancreatectomy Rats Rats, Wistar Vasodilation - drug effects Vasodilator Agents - pharmacology Vitamin E - pharmacology
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