Resveratrol induces pro-apoptotic endoplasmic reticulum stress in human colon cancer cells

Resveratrol (3,4',5 tri-hydroxystilbene), a naturally occurring polyphenolic compound highly enriched in grapes and red wine, has been shown to induce anti-proliferation and apoptosis of human cancer cell lines. Resveratrol-induced dose-dependent apoptotic cell death in colon carcinoma cells, w...

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Veröffentlicht in:	Oncology reports 2007-11, Vol.18 (5), p.1269-1273
Hauptverfasser:	PARK, Jong-Wook, KYUNG JIN WOO, LEE, Jung-Tae, JUN HEE LIM, LEE, Tae-Jin, SANG HYUN KIM, YUNG HYUN CHOI, TAEG KYU KWON
Format:	Artikel
Sprache:	eng
Schlagworte:	Anticarcinogenic Agents - pharmacology Apoptosis - drug effects Biological and medical sciences Blotting, Western Caspases - metabolism Colonic Neoplasms - drug therapy Colonic Neoplasms - metabolism DNA-Binding Proteins - genetics Endoplasmic Reticulum - drug effects Endoplasmic Reticulum - metabolism Eukaryotic Initiation Factor-2 - genetics Eukaryotic Initiation Factor-2 - metabolism Flow Cytometry Gastroenterology. Liver. Pancreas. Abdomen Heat-Shock Proteins - genetics Heat-Shock Proteins - metabolism HT29 Cells - drug effects Humans Medical sciences Molecular Chaperones - genetics Molecular Chaperones - metabolism Nuclear Proteins - genetics Phosphorylation - drug effects Regulatory Factor X Transcription Factors Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger - genetics RNA, Messenger - metabolism Stilbenes - pharmacology Stomach. Duodenum. Small intestine. Colon. Rectum. Anus Transcription Factor CHOP - genetics Transcription Factor CHOP - metabolism Transcription Factors Tumors X-Box Binding Protein 1
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