Disease Progression in Hutchinson-Gilford Progeria Syndrome: Impact on Growth and Development

Hutchinson-Gilford progeria syndrome is a rare and uniformly fatal segmental "premature aging" disease that affects a variety of organ systems. We sought to more clearly define the bone and weight abnormalities in patients with progeria as potential outcome parameters for prospective clini...

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Veröffentlicht in:	Pediatrics (Evanston) 2007-10, Vol.120 (4), p.824-833
Hauptverfasser:	Gordon, Leslie B, McCarten, Kathleen M, Giobbie-Hurder, Anita, Machan, Jason T, Campbell, Susan E, Berns, Scott D, Kieran, Mark W
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Aging Biological and medical sciences Body Weight Bone and Bones - abnormalities Bone Demineralization, Pathologic - genetics Bone Diseases, Developmental - genetics Bone Resorption - genetics Bones Child Child, Preschool Children & youth Contracture - genetics Development and progression Developmental biology Developmental Disabilities - genetics Disease Progression Diseases of the osteoarticular system Dysplasia Female Femur Head Necrosis - genetics General aspects Genotype & phenotype Humans Incisor - abnormalities Infant Infant, Newborn Joint Diseases - genetics Longitudinal Studies Male Medical sciences Osteoporosis. Osteomalacia. Paget disease Patient outcomes Pediatrics Physical growth Physiological aspects Progeria Progeria - genetics Prospective Studies Retrospective Studies Tooth Eruption Weight
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