Growth factor signalling in endocrine and anti-growth factor resistant breast cancer

Growth factors provide powerful mitogenic and survival signals to breast cancer cells and it is therefore not surprising that they are able to subvert inhibitory responses to anti-hormonal drugs. In this review we discuss several mechanisms by which this may be achieved and expand our observations t...

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Veröffentlicht in:	Reviews in endocrine & metabolic disorders 2007-09, Vol.8 (3), p.241-253
Hauptverfasser:	Nicholson, R I, Hutcheson, I R, Jones, H E, Hiscox, S E, Giles, M, Taylor, K M, Gee, J M W
Format:	Artikel
Sprache:	eng
Schlagworte:	Breast cancer Breast Neoplasms - physiopathology Female Humans Intercellular Signaling Peptides and Proteins - physiology Receptor, Epidermal Growth Factor - physiology Receptors, Estrogen - physiology Signal Transduction - physiology
Online-Zugang:	Volltext
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