p66 Shc Tumor Levels Show a Strong Prognostic Correlation with Disease Outcome in Stage IIA Colon Cancer

Purpose: Most stage IIA colon cancer patients receive no adjuvant therapy despite an estimated 15% risk of disease-related death within 5 years of resection. Prognostication of disease outcome would benefit the clinician by categorizing patients with stage IIA disease by risk. The abundance of the s...

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Veröffentlicht in:	Clinical cancer research 2007-10, Vol.13 (19), p.5798-5804
Hauptverfasser:	GROSSMAN, Steven R, LYLE, Stephen, HAFER, Laurie J, RESNICK, Murray B, SABO, Edmond, LIS, Rosina T, ROSINHA, Elizabeth, QIN LIU, HSIEH, Chung-Cheng, BHAT, Gajanan, FRACKELTON, A. Raymond
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptor Proteins, Signal Transducing - biosynthesis Adaptor Proteins, Signal Transducing - physiology Adult Aged Antineoplastic agents Biological and medical sciences Cohort Studies colon cancer Colonic Neoplasms - diagnosis Colonic Neoplasms - metabolism Disease Progression Female Gastroenterology. Liver. Pancreas. Abdomen Gene Expression Regulation, Neoplastic Humans Male Medical sciences Middle Aged Pharmacology. Drug treatments Prognosis prognostic marker Proportional Hazards Models Recurrence Shc Shc Signaling Adaptor Proteins Src Homology 2 Domain-Containing, Transforming Protein 1 Stomach. Duodenum. Small intestine. Colon. Rectum. Anus Treatment Outcome Tumors
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