Foot-and-mouth disease non-structural protein serology in cattle: Use of a Bayesian framework to estimate diagnostic sensitivity and specificity of six ELISA tests and true prevalence in the field

Abstract The diagnostic performance of six foot-and-mouth disease (FMD) assays for detection of antibodies to the non-structural proteins (NSP) of the FMD virus (FMDV) was estimated using a Bayesian analysis on field sera from cattle of unknown infection status originating from post-FMDV outbreak si...

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Veröffentlicht in:	Vaccine 2007-10, Vol.25 (41), p.7177-7196
Hauptverfasser:	Goris, N, Praet, N, Sammin, D, Yadin, H, Paton, D, Brocchi, E, Berkvens, D, De Clercq, K
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergy and Immunology Animal populations Animal viral diseases Animals Antibodies, Viral - blood Antigens, Viral Bayes Theorem Bayesian Biological and medical sciences Cattle Enzyme-Linked Immunosorbent Assay - methods Estimates Foot & mouth disease Foot-and-mouth disease Foot-and-Mouth Disease - diagnosis Foot-and-Mouth Disease - epidemiology Foot-and-Mouth Disease - immunology Foot-and-mouth disease virus Immunization Infections Infectious diseases Israel - epidemiology Medical sciences Non-structural protein Prevalence Sensitivity and Specificity Statistical methods Viral diseases Viral Nonstructural Proteins Zimbabwe - epidemiology
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