An Evaluation of Cyclooxygenase-2 as a Prognostic Biomarker in Mid-Gut Carcinoid Tumours

Background/Aims: Mid-gut carcinoids (MGC) are the most common of the gastrointestinal carcinoid tumours. There is a lack of reliable prognostic indicators for MGC. Cox-2 and Bcl-2 were evaluated as prognostic biomarkers in a cohort of well-characterised non-appendiceal MGC. Methods: Tissue from the...

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Veröffentlicht in:	Neuroendocrinology 2007-01, Vol.86 (2), p.104-111
Hauptverfasser:	Cadden, Ian, Johnston, Brian T., Turner, Graham, McCance, David, Ardill, Joy, McGinty, Ann
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Appendix - pathology Biological and medical sciences Biomarkers, Tumor - metabolism Carcinoid Tumor - metabolism Carcinoid Tumor - mortality Carcinoid Tumor - pathology Clinical Neuroendocrinology and Neuroendocrine Tumors Colon - pathology Cyclooxygenase 2 - metabolism Female Fundamental and applied biological sciences. Psychology Humans Intestinal Neoplasms - metabolism Intestinal Neoplasms - mortality Intestinal Neoplasms - pathology Intestine, Small - pathology Liver Neoplasms - metabolism Liver Neoplasms - secondary Male Middle Aged Prognosis Proportional Hazards Models Proto-Oncogene Proteins c-bcl-2 - metabolism Vertebrates: endocrinology
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