Effects of high-dose vitamin E supplementation on oxidative stress and microalbuminuria in young adult patients with childhood onset type 1 diabetes mellitus

Introduction The aim of this study was to evaluate the effects of high‐dose vitamin E supplementation (1200 mg/day) on reducing both microalbuminuria (MA) and oxidative stress in patients with type 1 diabetes mellitus (T1DM) and persistent MA. Methods We performed a 12‐month, randomized, placebo‐con...

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Veröffentlicht in:	Diabetes/metabolism research and reviews 2007-10, Vol.23 (7), p.539-546
Hauptverfasser:	Giannini, C., Lombardo, F., Currò, F., Pomilio, M., Bucciarelli, T., Chiarelli, F., Mohn, A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Age of Onset Albuminuria - drug therapy Albuminuria - prevention & control Biological and medical sciences Body Mass Index Child Creatinine - urine Cross-Over Studies Diabetes Mellitus, Type 1 - physiopathology Diabetes. Impaired glucose tolerance diabetic nephropathy Dietary Supplements Double-Blind Method Endocrine pancreas. Apud cells (diseases) Endocrinopathies Etiopathogenesis. Screening. Investigations. Target tissue resistance Female Fundamental and applied biological sciences. Psychology growth factors Humans Kidneys Lipoproteins, LDL - blood Lipoproteins, LDL - drug effects Male Medical sciences microalbuminuria Nephrology. Urinary tract diseases oxidative stress Oxidative Stress - drug effects Patient Selection Placebos type 1 diabetes mellitus Urinary system involvement in other diseases. Miscellaneous Vertebrates: endocrinology Vitamin E - administration & dosage Vitamin E - therapeutic use vitamin E supplementation
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