Brachytherapy Seed Localization Using Geometric and Linear Programming Techniques

We propose an optimization algorithm to solve the brachytherapy seed localization problem in prostate brachytherapy. Our algorithm is based on novel geometric approaches to exploit the special structure of the problem and relies on a number of key observations which help us formulate the optimizatio...

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Veröffentlicht in:IEEE transactions on medical imaging 2007-09, Vol.26 (9), p.1291-1304
Hauptverfasser: Singh, V., Mukherjee, L., Jinhui Xu, Hoffmann, K.R., Dinu, P.M., Podgorsak, M.
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container_end_page 1304
container_issue 9
container_start_page 1291
container_title IEEE transactions on medical imaging
container_volume 26
creator Singh, V.
Mukherjee, L.
Jinhui Xu
Hoffmann, K.R.
Dinu, P.M.
Podgorsak, M.
description We propose an optimization algorithm to solve the brachytherapy seed localization problem in prostate brachytherapy. Our algorithm is based on novel geometric approaches to exploit the special structure of the problem and relies on a number of key observations which help us formulate the optimization problem as a minimization integer program (IP). Our IP model precisely defines the feasibility polyhedron for this problem using a polynomial number of half-spaces; the solution to its corresponding linear program is rounded to yield an integral solution to our task of determining correspondences between seeds in multiple projection images. The algorithm is efficient in theory as well as in practice and performs well on simulation data (~98% accuracy) and real X-ray images (~95% accuracy). We present in detail the underlying ideas and an extensive set of performance evaluations based on our implementation.
doi_str_mv 10.1109/TMI.2007.900740
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subjects Accuracy
Algorithms
Artificial Intelligence
Brachytherapy
Brachytherapy - instrumentation
Brachytherapy - methods
Brachytherapy seed localization (BSL)
Cancer
Computer science
geometric optimization
Humans
Imaging, Three-Dimensional - methods
Implants
Information Storage and Retrieval - methods
integer programming
Linear programming
Localization
Male
Mathematical models
Medical treatment
Minimization methods
multiview point correspondence
Neoplasms
Optimization
Pattern Recognition, Automated - methods
Polynomials
Position (location)
Programming, Linear
Prostatic Neoplasms - diagnostic imaging
Prostatic Neoplasms - radiotherapy
Prosthesis Implantation - methods
Radiographic Image Enhancement - methods
Radiographic Image Interpretation, Computer-Assisted - methods
Radiotherapy, Computer-Assisted - methods
Reproducibility of Results
Seeds
Sensitivity and Specificity
X-ray imaging
title Brachytherapy Seed Localization Using Geometric and Linear Programming Techniques
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