Development of an ex vivo cellular model of rheumatoid arthritis: Critical role of cd14‐positive monocyte/macrophages in the development of pannus tissue

Objective To establish an ex vivo cellular model of pannus, the aberrant overgrowth of human synovial tissue (ST). Methods Inflammatory cells that infiltrated pannus tissue from patients with rheumatoid arthritis (RA) were collected without enzyme digestion, and designated as ST‐derived inflammatory...

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Veröffentlicht in:	Arthritis and rheumatism 2007-09, Vol.56 (9), p.2875-2885
Hauptverfasser:	Nozaki, Toshiko, Takahashi, Kyoko, Ishii, Osamu, Endo, Sachio, Hioki, Kyoji, Mori, Toshihito, Kikukawa, Tadahiro, Boumpas, Dimitrios T., Ozaki, Shoichi, Yamada, Hidehiro
Format:	Artikel
Sprache:	eng
Schlagworte:	Arthritis, Rheumatoid - immunology Arthritis, Rheumatoid - pathology Biological and medical sciences Cells, Cultured Connective Tissue - pathology Diseases of the osteoarticular system Humans Inflammatory joint diseases Lipopolysaccharide Receptors Macrophages - immunology Medical sciences Models, Biological Monocytes - immunology
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