Molecular indices of apoptosis activation in elastase-induced aneurysms after embolization with platinum coils

Even though endovascular coils have been widely used for the treatment of intracranial aneurysms, the cellular and molecular responses of aneurysms to the coils after embolization remain poorly understood. The aim of the present study was to understand the mechanism of apoptosis in aneurysms emboliz...

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Veröffentlicht in:	Stroke (1970) 2007-10, Vol.38 (10), p.2787-2794
Hauptverfasser:	KADIRVEL, Ramanathan, DING, Yong-Hong, DAYING DAI, LEWIS, Debra A, CLOFT, Harry J, KALLMES, David F
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis - physiology Biological and medical sciences Carotid Artery, Common - pathology Caspase 3 - metabolism Caspase 8 - metabolism Caspase 9 - metabolism Cerebral circulation. Blood-brain barrier. Choroid plexus. Cerebrospinal fluid. Circumventricular organ. Meninges Disease Models, Animal Diseases of the nervous system Embolization, Therapeutic - instrumentation Embolization, Therapeutic - methods Fibroblasts - metabolism Fibroblasts - pathology Fundamental and applied biological sciences. Psychology In Situ Nick-End Labeling Intracranial Aneurysm - metabolism Intracranial Aneurysm - pathology Intracranial Aneurysm - therapy Medical sciences Neurology Pancreatic Elastase Platinum Proto-Oncogene Proteins c-bcl-2 - metabolism Rabbits Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects) Tumor Necrosis Factor-alpha - metabolism Vascular diseases and vascular malformations of the nervous system Vertebrates: nervous system and sense organs
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