Altered expression of sodium transporters in ischemic penumbra after focal cerebral ischemia in rats

This study was aimed to examine whether the changes of protein expression of sodium transporters in the ischemic penumbra are associated with the pathogenesis of ischemia-induced brain edema and/or brain cell injury. An experimental model of cerebral ischemia was made by permanent middle cerebral ar...

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Veröffentlicht in:	Neuroscience research 2007-10, Vol.59 (2), p.152-159
Hauptverfasser:	Jung, Yong-Wook, Choi, In-Jang, Kwon, Tae-Hwan
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Brain edema Brain Edema - etiology Brain Edema - metabolism Brain Edema - physiopathology Brain ischemia Brain Ischemia - metabolism Brain Ischemia - physiopathology Calcium - metabolism Calcium Signaling - physiology Carrier Proteins - metabolism Cerebral Infarction - metabolism Cerebral Infarction - physiopathology Cerebrum - metabolism Cerebrum - physiopathology Down-Regulation - physiology Glial Fibrillary Acidic Protein - metabolism Immunoblotting Infarction, Middle Cerebral Artery - metabolism Infarction, Middle Cerebral Artery - physiopathology Intracellular acidosis Ischemic penumbra Male Nerve Tissue Proteins - metabolism Nuclear Proteins - metabolism Rats Rats, Sprague-Dawley Sodium - metabolism Sodium transporters Sodium-Bicarbonate Symporters - metabolism Sodium-Calcium Exchanger - metabolism Sodium-Hydrogen Exchanger 1 Sodium-Hydrogen Exchangers - metabolism Sodium-Potassium-Exchanging ATPase - metabolism Targeted proteomics Up-Regulation - physiology Water-Electrolyte Balance - physiology
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