Metastasis to the thyroid gland : unusual site of metastasis
Background : The incidence of metastasis to the thyroid gland in autopsy series varies from 1.25 % to 24 %. Metastasis to the thyroid gland is usually considered as a terminal event, and the effectiveness of conventional treatment has been questioned. Methods : Seven patients with metastasis to the...
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| Veröffentlicht in: | Journal of Egyptian National Cancer Institute 2006-03, Vol.18 (1), p.67-72 |
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| creator | Jirjis, Amani S. Shihatah, Sami R. Jawdah, Iman A. |
| description | Background : The incidence of metastasis to the thyroid
gland in autopsy series varies from 1.25 % to 24 %.
Metastasis to the thyroid gland is usually considered as
a terminal event, and the effectiveness of conventional
treatment has been questioned.
Methods : Seven patients with metastasis to the thyroid
gland were studied retrospectively. Primary tumor origin
was identified in all of them. Metastasis to the thyroid
gland was confirmed by fine needle aspiration cytology
or histology. Data were analyzed for the type of malignant
lesions, the clinical course of the disease, and the prognosis
after thyroid involvement.
Results : Two patients had lung as a primary tumor
site. Breast, iris, kidney, parotid and soft tissue sarcoma
were the involved primary sites in the other cases. The
time from the diagnosis of primary tumor to metastasis
to the thyroid gland was considerable (ranged from 13-
135 months, median 60 months). Fine needle aspiration
cytology detected metastasis in five of seven patients.
Treatment was surgery alone or surgery with adjuvant
therapy. One patient didn't receive any treatment.
Conclusions : In any patient with a previous history
of malignancy, no matter how old that history is, a new
thyroid mass should be considered as recurrence until
proved otherwise. Although detection of metastasis to the
thyroid gland often indicates poor prognosis, aggressive
surgical and medical therapy may be effective in a small
percentage of patients. |
| format | Article |
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gland in autopsy series varies from 1.25 % to 24 %.
Metastasis to the thyroid gland is usually considered as
a terminal event, and the effectiveness of conventional
treatment has been questioned.
Methods : Seven patients with metastasis to the thyroid
gland were studied retrospectively. Primary tumor origin
was identified in all of them. Metastasis to the thyroid
gland was confirmed by fine needle aspiration cytology
or histology. Data were analyzed for the type of malignant
lesions, the clinical course of the disease, and the prognosis
after thyroid involvement.
Results : Two patients had lung as a primary tumor
site. Breast, iris, kidney, parotid and soft tissue sarcoma
were the involved primary sites in the other cases. The
time from the diagnosis of primary tumor to metastasis
to the thyroid gland was considerable (ranged from 13-
135 months, median 60 months). Fine needle aspiration
cytology detected metastasis in five of seven patients.
Treatment was surgery alone or surgery with adjuvant
therapy. One patient didn't receive any treatment.
Conclusions : In any patient with a previous history
of malignancy, no matter how old that history is, a new
thyroid mass should be considered as recurrence until
proved otherwise. Although detection of metastasis to the
thyroid gland often indicates poor prognosis, aggressive
surgical and medical therapy may be effective in a small
percentage of patients.</description><identifier>ISSN: 1110-0362</identifier><identifier>EISSN: 1687-9996</identifier><identifier>PMID: 17237852</identifier><language>eng</language><publisher>Cairo, Egypt: Cairo University, National Cancer Institute</publisher><subject>Adult ; Aged ; Biopsy, Fine-Needle ; Breast Neoplasms - pathology ; Bronchial Neoplasms - pathology ; Cancer ; Female ; Humans ; Kidney Neoplasms - pathology ; Male ; Middle Aged ; Neoplasm Metastasis - diagnosis ; Parotid Neoplasms - pathology ; Retrospective Studies ; Thyroid gland ; Thyroid Neoplasms - diagnosis ; Thyroid Neoplasms - secondary ; Thyroid Neoplasms - therapy ; الأمراض ; الأورام ; السرطان ; الغدة الدرقية</subject><ispartof>Journal of Egyptian National Cancer Institute, 2006-03, Vol.18 (1), p.67-72</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>315,781,785</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/17237852$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Jirjis, Amani S.</creatorcontrib><creatorcontrib>Shihatah, Sami R.</creatorcontrib><creatorcontrib>Jawdah, Iman A.</creatorcontrib><title>Metastasis to the thyroid gland : unusual site of metastasis</title><title>Journal of Egyptian National Cancer Institute</title><addtitle>J Egypt Natl Canc Inst</addtitle><description>Background : The incidence of metastasis to the thyroid
gland in autopsy series varies from 1.25 % to 24 %.
Metastasis to the thyroid gland is usually considered as
a terminal event, and the effectiveness of conventional
treatment has been questioned.
Methods : Seven patients with metastasis to the thyroid
gland were studied retrospectively. Primary tumor origin
was identified in all of them. Metastasis to the thyroid
gland was confirmed by fine needle aspiration cytology
or histology. Data were analyzed for the type of malignant
lesions, the clinical course of the disease, and the prognosis
after thyroid involvement.
Results : Two patients had lung as a primary tumor
site. Breast, iris, kidney, parotid and soft tissue sarcoma
were the involved primary sites in the other cases. The
time from the diagnosis of primary tumor to metastasis
to the thyroid gland was considerable (ranged from 13-
135 months, median 60 months). Fine needle aspiration
cytology detected metastasis in five of seven patients.
Treatment was surgery alone or surgery with adjuvant
therapy. One patient didn't receive any treatment.
Conclusions : In any patient with a previous history
of malignancy, no matter how old that history is, a new
thyroid mass should be considered as recurrence until
proved otherwise. Although detection of metastasis to the
thyroid gland often indicates poor prognosis, aggressive
surgical and medical therapy may be effective in a small
percentage of patients.</description><subject>Adult</subject><subject>Aged</subject><subject>Biopsy, Fine-Needle</subject><subject>Breast Neoplasms - pathology</subject><subject>Bronchial Neoplasms - pathology</subject><subject>Cancer</subject><subject>Female</subject><subject>Humans</subject><subject>Kidney Neoplasms - pathology</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Neoplasm Metastasis - diagnosis</subject><subject>Parotid Neoplasms - pathology</subject><subject>Retrospective Studies</subject><subject>Thyroid gland</subject><subject>Thyroid Neoplasms - diagnosis</subject><subject>Thyroid Neoplasms - secondary</subject><subject>Thyroid Neoplasms - therapy</subject><subject>الأمراض</subject><subject>الأورام</subject><subject>السرطان</subject><subject>الغدة الدرقية</subject><issn>1110-0362</issn><issn>1687-9996</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2006</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9j1tLAzEQhYNUbK3-A5E89S2Q2-YivkjxBhVf9HlJNrO6stutm-Sh_95Aa-EMcxi-GeacoQVTRhNrrZoVzxglVCg-R5cx_lCqFNXVBZozzYU2FV-g-zdILhZ1EacRp28otZ_GLuCv3m0DvsN5m2N2PY5dAjy2eDhtXKHz1vURro99iT6fHj_WL2Tz_vy6ftgQYLJKRFNayZY7HYwNwYFnjVfMBe9b75k2WgrRuMC5bQT4oByIxioheQhaSFBiiVaHu7tp_M0QUz10sYG-PAhjjrUy3EpFbQFvj2D2A4R6N3WDm_b1f94C3BwAKHNo3Ynglhkh_gAeKFxx</recordid><startdate>200603</startdate><enddate>200603</enddate><creator>Jirjis, Amani S.</creator><creator>Shihatah, Sami R.</creator><creator>Jawdah, Iman A.</creator><general>Cairo University, National Cancer Institute</general><scope>ADJCN</scope><scope>AHFXO</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>200603</creationdate><title>Metastasis to the thyroid gland : unusual site of metastasis</title><author>Jirjis, Amani S. ; Shihatah, Sami R. ; Jawdah, Iman A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-e145t-70054f2a7d89ddaeb1cb61adbbfbb1787433cad229c3ebd6ae3c96342dd734e63</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2006</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Biopsy, Fine-Needle</topic><topic>Breast Neoplasms - pathology</topic><topic>Bronchial Neoplasms - pathology</topic><topic>Cancer</topic><topic>Female</topic><topic>Humans</topic><topic>Kidney Neoplasms - pathology</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Neoplasm Metastasis - diagnosis</topic><topic>Parotid Neoplasms - pathology</topic><topic>Retrospective Studies</topic><topic>Thyroid gland</topic><topic>Thyroid Neoplasms - diagnosis</topic><topic>Thyroid Neoplasms - secondary</topic><topic>Thyroid Neoplasms - therapy</topic><topic>الأمراض</topic><topic>الأورام</topic><topic>السرطان</topic><topic>الغدة الدرقية</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Jirjis, Amani S.</creatorcontrib><creatorcontrib>Shihatah, Sami R.</creatorcontrib><creatorcontrib>Jawdah, Iman A.</creatorcontrib><collection>الدوريات العلمية والإحصائية - e-Marefa Academic and Statistical Periodicals</collection><collection>معرفة - المحتوى العربي الأكاديمي المتكامل - e-Marefa Academic Complete</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of Egyptian National Cancer Institute</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Jirjis, Amani S.</au><au>Shihatah, Sami R.</au><au>Jawdah, Iman A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Metastasis to the thyroid gland : unusual site of metastasis</atitle><jtitle>Journal of Egyptian National Cancer Institute</jtitle><addtitle>J Egypt Natl Canc Inst</addtitle><date>2006-03</date><risdate>2006</risdate><volume>18</volume><issue>1</issue><spage>67</spage><epage>72</epage><pages>67-72</pages><issn>1110-0362</issn><eissn>1687-9996</eissn><abstract>Background : The incidence of metastasis to the thyroid
gland in autopsy series varies from 1.25 % to 24 %.
Metastasis to the thyroid gland is usually considered as
a terminal event, and the effectiveness of conventional
treatment has been questioned.
Methods : Seven patients with metastasis to the thyroid
gland were studied retrospectively. Primary tumor origin
was identified in all of them. Metastasis to the thyroid
gland was confirmed by fine needle aspiration cytology
or histology. Data were analyzed for the type of malignant
lesions, the clinical course of the disease, and the prognosis
after thyroid involvement.
Results : Two patients had lung as a primary tumor
site. Breast, iris, kidney, parotid and soft tissue sarcoma
were the involved primary sites in the other cases. The
time from the diagnosis of primary tumor to metastasis
to the thyroid gland was considerable (ranged from 13-
135 months, median 60 months). Fine needle aspiration
cytology detected metastasis in five of seven patients.
Treatment was surgery alone or surgery with adjuvant
therapy. One patient didn't receive any treatment.
Conclusions : In any patient with a previous history
of malignancy, no matter how old that history is, a new
thyroid mass should be considered as recurrence until
proved otherwise. Although detection of metastasis to the
thyroid gland often indicates poor prognosis, aggressive
surgical and medical therapy may be effective in a small
percentage of patients.</abstract><cop>Cairo, Egypt</cop><pub>Cairo University, National Cancer Institute</pub><pmid>17237852</pmid><tpages>6</tpages></addata></record> |
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| ispartof | Journal of Egyptian National Cancer Institute, 2006-03, Vol.18 (1), p.67-72 |
| issn | 1110-0362 1687-9996 |
| language | eng |
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| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
| subjects | Adult Aged Biopsy, Fine-Needle Breast Neoplasms - pathology Bronchial Neoplasms - pathology Cancer Female Humans Kidney Neoplasms - pathology Male Middle Aged Neoplasm Metastasis - diagnosis Parotid Neoplasms - pathology Retrospective Studies Thyroid gland Thyroid Neoplasms - diagnosis Thyroid Neoplasms - secondary Thyroid Neoplasms - therapy الأمراض الأورام السرطان الغدة الدرقية |
| title | Metastasis to the thyroid gland : unusual site of metastasis |
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