Palivizumab Treatment of Respiratory Syncytial Virus Infection after Allogeneic Hematopoietic Stem Cell Transplantation
Among 40 allogeneic stem cell transplant recipients who developed symptomatic respiratory syncytial virus infection, including 22 patients with lower respiratory tract infection, 19 received palivizumab (9 of whom had upper respiratory tract disease). Palivizumab did not prevent progression to lower...
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Veröffentlicht in: | Clinical infectious diseases 2007-10, Vol.45 (8), p.1019-1024 |
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creator | de Fontbrune, Flore Sicre Robin, Marie Porcher, Raphael Scieux, Catherine de Latour, Régis Peffault Ferry, Christèle Rocha, Vanderson Boudjedir, Karim Devergie, Agnès Bergeron, Anne Gluckman, Eliane Azoulay, Elie Lapalu, Jordane Socié, Gérard Ribaud, Patricia |
description | Among 40 allogeneic stem cell transplant recipients who developed symptomatic respiratory syncytial virus infection, including 22 patients with lower respiratory tract infection, 19 received palivizumab (9 of whom had upper respiratory tract disease). Palivizumab did not prevent progression to lower respiratory infection and had no impact on the overall survival rate. |
doi_str_mv | 10.1086/521912 |
format | Article |
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Palivizumab did not prevent progression to lower respiratory infection and had no impact on the overall survival rate.</description><identifier>ISSN: 1058-4838</identifier><identifier>EISSN: 1537-6591</identifier><identifier>DOI: 10.1086/521912</identifier><identifier>PMID: 17879919</identifier><identifier>CODEN: CIDIEL</identifier><language>eng</language><publisher>Chicago, IL: The University of Chicago Press</publisher><subject>Adolescent ; Adult ; Aged ; Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy ; Antibodies, Monoclonal - therapeutic use ; Antibodies, Monoclonal, Humanized ; Antiviral Agents - therapeutic use ; Biological and medical sciences ; Blood donation ; Bone marrow ; Bone marrow, stem cells transplantation. Graft versus host reaction ; Brief Reports ; Child ; Child, Preschool ; Cord blood ; Hematologic Diseases - complications ; Hematopoietic Stem Cell Transplantation ; Human respiratory syncytial virus ; Human viral diseases ; Humans ; Immunomodulators ; Infections ; Infectious diseases ; Medical sciences ; Middle Aged ; Monoclonal antibodies ; Mortality ; Palivizumab ; Pharmacology. Drug treatments ; Pneumonia - drug therapy ; Pneumonia - virology ; Respiratory diseases ; Respiratory syncytial virus ; Respiratory syncytial virus infections ; Respiratory Syncytial Virus Infections - drug therapy ; Respiratory syncytial viruses ; Respiratory tract infections ; Respiratory Tract Infections - drug therapy ; Respiratory Tract Infections - virology ; Retrospective Studies ; Stem cells ; Survival Analysis ; Transfusions. Complications. Transfusion reactions. Cell and gene therapy ; Transplants & implants ; Viral diseases ; Viral diseases of the respiratory system and ent viral diseases ; Viruses</subject><ispartof>Clinical infectious diseases, 2007-10, Vol.45 (8), p.1019-1024</ispartof><rights>Copyright 2007 The Infectious Diseases Society of America</rights><rights>2007 of the Infectious Diseases Society of America 2007</rights><rights>2008 INIST-CNRS</rights><rights>Copyright University of Chicago, acting through its Press Oct 15, 2007</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c548t-daa85d3376b7b3389b247df99cf2bafa578ec0be00ffe5759a23283c50a060883</citedby><cites>FETCH-LOGICAL-c548t-daa85d3376b7b3389b247df99cf2bafa578ec0be00ffe5759a23283c50a060883</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.jstor.org/stable/pdf/4485632$$EPDF$$P50$$Gjstor$$H</linktopdf><linktohtml>$$Uhttps://www.jstor.org/stable/4485632$$EHTML$$P50$$Gjstor$$H</linktohtml><link.rule.ids>314,780,784,803,27923,27924,58016,58249</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=20289792$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/17879919$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>de Fontbrune, Flore Sicre</creatorcontrib><creatorcontrib>Robin, Marie</creatorcontrib><creatorcontrib>Porcher, Raphael</creatorcontrib><creatorcontrib>Scieux, Catherine</creatorcontrib><creatorcontrib>de Latour, Régis Peffault</creatorcontrib><creatorcontrib>Ferry, Christèle</creatorcontrib><creatorcontrib>Rocha, Vanderson</creatorcontrib><creatorcontrib>Boudjedir, Karim</creatorcontrib><creatorcontrib>Devergie, Agnès</creatorcontrib><creatorcontrib>Bergeron, Anne</creatorcontrib><creatorcontrib>Gluckman, Eliane</creatorcontrib><creatorcontrib>Azoulay, Elie</creatorcontrib><creatorcontrib>Lapalu, Jordane</creatorcontrib><creatorcontrib>Socié, Gérard</creatorcontrib><creatorcontrib>Ribaud, Patricia</creatorcontrib><title>Palivizumab Treatment of Respiratory Syncytial Virus Infection after Allogeneic Hematopoietic Stem Cell Transplantation</title><title>Clinical infectious diseases</title><addtitle>Clinical Infectious Diseases</addtitle><addtitle>Clinical Infectious Diseases</addtitle><description>Among 40 allogeneic stem cell transplant recipients who developed symptomatic respiratory syncytial virus infection, including 22 patients with lower respiratory tract infection, 19 received palivizumab (9 of whom had upper respiratory tract disease). Palivizumab did not prevent progression to lower respiratory infection and had no impact on the overall survival rate.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</subject><subject>Antibodies, Monoclonal - therapeutic use</subject><subject>Antibodies, Monoclonal, Humanized</subject><subject>Antiviral Agents - therapeutic use</subject><subject>Biological and medical sciences</subject><subject>Blood donation</subject><subject>Bone marrow</subject><subject>Bone marrow, stem cells transplantation. Graft versus host reaction</subject><subject>Brief Reports</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Cord blood</subject><subject>Hematologic Diseases - complications</subject><subject>Hematopoietic Stem Cell Transplantation</subject><subject>Human respiratory syncytial virus</subject><subject>Human viral diseases</subject><subject>Humans</subject><subject>Immunomodulators</subject><subject>Infections</subject><subject>Infectious diseases</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Monoclonal antibodies</subject><subject>Mortality</subject><subject>Palivizumab</subject><subject>Pharmacology. Drug treatments</subject><subject>Pneumonia - drug therapy</subject><subject>Pneumonia - virology</subject><subject>Respiratory diseases</subject><subject>Respiratory syncytial virus</subject><subject>Respiratory syncytial virus infections</subject><subject>Respiratory Syncytial Virus Infections - drug therapy</subject><subject>Respiratory syncytial viruses</subject><subject>Respiratory tract infections</subject><subject>Respiratory Tract Infections - drug therapy</subject><subject>Respiratory Tract Infections - virology</subject><subject>Retrospective Studies</subject><subject>Stem cells</subject><subject>Survival Analysis</subject><subject>Transfusions. Complications. Transfusion reactions. Cell and gene therapy</subject><subject>Transplants & implants</subject><subject>Viral diseases</subject><subject>Viral diseases of the respiratory system and ent viral diseases</subject><subject>Viruses</subject><issn>1058-4838</issn><issn>1537-6591</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2007</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkV2L1DAUhoso7of6C0SqoHfVfDRNcrmMu87Cgqs7fuBNOM0kkrFtapKq4683Q4dZEMSrnPA-5z3JeYviEUYvMRLNK0awxOROcYwZ5VXDJL6ba8REVQsqjoqTGDcIYSwQu18cYS64lFgeFz-voXM_3O-ph7ZcBQOpN0MqvS3fmzi6AMmHbXmzHfQ2OejKjy5MsbwcrNHJ-aEEm0woz7rOfzWDcbpcmj73jN6ZlG83yfTlwnRd9oYhjh0MCXaND4p7FrpoHu7P0-LDxflqsayu3r65XJxdVZrVIlVrAMHWlPKm5S2lQrak5msrpbakBQuMC6NRaxCy1jDOJBBKBNUMAWqQEPS0eDH7jsF_n0xMqndR5wfBYPwUVSOIxIzJ_4IECSkbjjP47C9w46cw5E-onIEUtOH1rZsOPsZgrBqD6yFsFUZqF5iaA8vgk73b1PZmfYvtE8rA8z0AUUNn8xq1iweOICIklzujpzPnp_Hfwx7PzCbmWA9UXQvW0J1czbKLyfw6yBC-qYZTztTy8xf1ieBr9m51oV7TP-kBwJc</recordid><startdate>20071015</startdate><enddate>20071015</enddate><creator>de Fontbrune, Flore Sicre</creator><creator>Robin, Marie</creator><creator>Porcher, Raphael</creator><creator>Scieux, Catherine</creator><creator>de Latour, Régis Peffault</creator><creator>Ferry, Christèle</creator><creator>Rocha, Vanderson</creator><creator>Boudjedir, Karim</creator><creator>Devergie, Agnès</creator><creator>Bergeron, Anne</creator><creator>Gluckman, Eliane</creator><creator>Azoulay, Elie</creator><creator>Lapalu, Jordane</creator><creator>Socié, Gérard</creator><creator>Ribaud, Patricia</creator><general>The University of Chicago Press</general><general>University of Chicago Press</general><general>Oxford University Press</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QL</scope><scope>7T2</scope><scope>7T7</scope><scope>7U7</scope><scope>7U9</scope><scope>8FD</scope><scope>C1K</scope><scope>FR3</scope><scope>H94</scope><scope>K9.</scope><scope>M7N</scope><scope>P64</scope><scope>7X8</scope></search><sort><creationdate>20071015</creationdate><title>Palivizumab Treatment of Respiratory Syncytial Virus Infection after Allogeneic Hematopoietic Stem Cell Transplantation</title><author>de Fontbrune, Flore Sicre ; Robin, Marie ; Porcher, Raphael ; Scieux, Catherine ; de Latour, Régis Peffault ; Ferry, Christèle ; Rocha, Vanderson ; Boudjedir, Karim ; Devergie, Agnès ; Bergeron, Anne ; Gluckman, Eliane ; Azoulay, Elie ; Lapalu, Jordane ; Socié, Gérard ; Ribaud, Patricia</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c548t-daa85d3376b7b3389b247df99cf2bafa578ec0be00ffe5759a23283c50a060883</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2007</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Aged</topic><topic>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</topic><topic>Antibodies, Monoclonal - therapeutic use</topic><topic>Antibodies, Monoclonal, Humanized</topic><topic>Antiviral Agents - therapeutic use</topic><topic>Biological and medical sciences</topic><topic>Blood donation</topic><topic>Bone marrow</topic><topic>Bone marrow, stem cells transplantation. Graft versus host reaction</topic><topic>Brief Reports</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>Cord blood</topic><topic>Hematologic Diseases - complications</topic><topic>Hematopoietic Stem Cell Transplantation</topic><topic>Human respiratory syncytial virus</topic><topic>Human viral diseases</topic><topic>Humans</topic><topic>Immunomodulators</topic><topic>Infections</topic><topic>Infectious diseases</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Monoclonal antibodies</topic><topic>Mortality</topic><topic>Palivizumab</topic><topic>Pharmacology. 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Palivizumab did not prevent progression to lower respiratory infection and had no impact on the overall survival rate.</abstract><cop>Chicago, IL</cop><pub>The University of Chicago Press</pub><pmid>17879919</pmid><doi>10.1086/521912</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
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source | MEDLINE; JSTOR Archive Collection A-Z Listing; Oxford University Press Journals All Titles (1996-Current); EZB-FREE-00999 freely available EZB journals |
subjects | Adolescent Adult Aged Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Antibodies, Monoclonal - therapeutic use Antibodies, Monoclonal, Humanized Antiviral Agents - therapeutic use Biological and medical sciences Blood donation Bone marrow Bone marrow, stem cells transplantation. Graft versus host reaction Brief Reports Child Child, Preschool Cord blood Hematologic Diseases - complications Hematopoietic Stem Cell Transplantation Human respiratory syncytial virus Human viral diseases Humans Immunomodulators Infections Infectious diseases Medical sciences Middle Aged Monoclonal antibodies Mortality Palivizumab Pharmacology. Drug treatments Pneumonia - drug therapy Pneumonia - virology Respiratory diseases Respiratory syncytial virus Respiratory syncytial virus infections Respiratory Syncytial Virus Infections - drug therapy Respiratory syncytial viruses Respiratory tract infections Respiratory Tract Infections - drug therapy Respiratory Tract Infections - virology Retrospective Studies Stem cells Survival Analysis Transfusions. Complications. Transfusion reactions. Cell and gene therapy Transplants & implants Viral diseases Viral diseases of the respiratory system and ent viral diseases Viruses |
title | Palivizumab Treatment of Respiratory Syncytial Virus Infection after Allogeneic Hematopoietic Stem Cell Transplantation |
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