Retropharyngeal neuroblastoma in a neonate: case report and literature review
Primary cervical neuroblastoma (NB) in neonates is extremely rare. We treated a 1-day-old male neonate who presented with stridor and feeding difficulty and was subsequently diagnosed with NB of the retropharynx. The tumor was excised in toto transorally, and no metastatic lesions were confirmed. Hi...
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| Veröffentlicht in: | Pediatric surgery international 2007-10, Vol.23 (10), p.1023-1026 |
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| container_title | Pediatric surgery international |
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| creator | Okazaki, Tadaharu Ohshita, Masaaki Furukawa, Masayuki Ikeda, Katsuhisa Ozaki, Yutaka Lane, Geoffrey J Yamataka, Atsuyuki |
| description | Primary cervical neuroblastoma (NB) in neonates is extremely rare. We treated a 1-day-old male neonate who presented with stridor and feeding difficulty and was subsequently diagnosed with NB of the retropharynx. The tumor was excised in toto transorally, and no metastatic lesions were confirmed. Histopathology and molecular genetic analysis showed poorly differentiated NB with no N-myc amplification, stage I NB. He has had no signs of recurrence or adverse sequelae during 18 months of follow-up. We report our experience and review the literature. |
| doi_str_mv | 10.1007/s00383-007-1990-y |
| format | Article |
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We treated a 1-day-old male neonate who presented with stridor and feeding difficulty and was subsequently diagnosed with NB of the retropharynx. The tumor was excised in toto transorally, and no metastatic lesions were confirmed. Histopathology and molecular genetic analysis showed poorly differentiated NB with no N-myc amplification, stage I NB. He has had no signs of recurrence or adverse sequelae during 18 months of follow-up. 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We treated a 1-day-old male neonate who presented with stridor and feeding difficulty and was subsequently diagnosed with NB of the retropharynx. The tumor was excised in toto transorally, and no metastatic lesions were confirmed. Histopathology and molecular genetic analysis showed poorly differentiated NB with no N-myc amplification, stage I NB. He has had no signs of recurrence or adverse sequelae during 18 months of follow-up. We report our experience and review the literature.</abstract><cop>Germany</cop><pub>Springer Nature B.V</pub><pmid>17661061</pmid><doi>10.1007/s00383-007-1990-y</doi><tpages>4</tpages></addata></record> |
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| source | MEDLINE; Springer Nature - Complete Springer Journals |
| subjects | Combined Modality Therapy Genes, myc - genetics Humans Infant, Newborn Male Neuroblastoma - diagnosis Neuroblastoma - genetics Neuroblastoma - pathology Neuroblastoma - therapy Pharyngeal Neoplasms - diagnosis Pharyngeal Neoplasms - genetics Pharyngeal Neoplasms - pathology Pharyngeal Neoplasms - therapy |
| title | Retropharyngeal neuroblastoma in a neonate: case report and literature review |
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