Characterization of β-Ketoadipate Pathway from Multi-Drug Resistance Bacterium, Acinetobacter baumannii DU202 by Proteomic Approach

In this study, the biodegradative activities of monocyclic aromatic compounds were determined from the multi-drug resistant (MDR) Acinetobacter baumannii, which were studied in the form of clinical isolates from a hospital in Korea. These bacteria were capable of biodegrading monocyclic aromatic com...

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Veröffentlicht in:	The journal of microbiology 2006-12, Vol.44 (6), p.632-640
Hauptverfasser:	Park, S.H. (Korea Basic Science Institute, Daejeon, Republic of Korea), Kim, J.W. (Dong-A University, Busan, Republic of Korea), Yun, S.H. (Korea Basic Science Institute, Daejeon, Republic of Korea), Leem, S.H. (Dong-A University, Busan, Republic of Korea), Kahng, H.Y. (Sunchon National University, Sunchon, Republic of Korea), Kim, S.I. (Korea Basic Science Institute, Daejeon, Republic of Korea), E-mail: ksi@kbsi.re.kr
Format:	Artikel
Sprache:	eng
Schlagworte:	Acinetobacter Acinetobacter baumannii Acinetobacter baumannii - drug effects Acinetobacter baumannii - genetics Acinetobacter baumannii - growth & development Acinetobacter baumannii - metabolism Adipates - metabolism Aged Amino Acid Sequence Anti-Bacterial Agents - pharmacology Aromatic compound biodegradation BACTERIA Bacterial Proteins - chemistry Bacterial Proteins - genetics Bacterial Proteins - metabolism Benzoates - metabolism beta-Ketoadipate Pathway Drug Resistance, Multiple, Bacterial Gene Expression Regulation, Bacterial Humans MDR Acinetobacter baumannii Microbial Sensitivity Tests Middle Aged Molecular Sequence Data Parabens - metabolism Proteome
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Zusammenfassung:	In this study, the biodegradative activities of monocyclic aromatic compounds were determined from the multi-drug resistant (MDR) Acinetobacter baumannii, which were studied in the form of clinical isolates from a hospital in Korea. These bacteria were capable of biodegrading monocyclic aromatic compounds, such as benzoate and p-hydroxybenzoate. In order to determine which pathways are available for biodegradation in these stains, we conducted proteome analyses of benzoate, and p-hydroxybenzoate-cultured A. baumannii DU202, using 2-DE/MS analysis.
ISSN:	1225-8873 1976-3794