Mutation of the epidermal growth factor receptor gene in the development of adenocarcinoma of the lung

Summary Recently, a mutation of the epidermal growth factor receptor (EGFR) gene has been reported to be implicated in the development of pulmonary adenocarcinoma. However, the involvement of the mutation in atypical adenomatous hyperplasia (AAH) and multiple adenocarcinomas still remains unclear. W...

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Veröffentlicht in:	Lung cancer (Amsterdam, Netherlands) Netherlands), 2007-10, Vol.58 (1), p.30-35
Hauptverfasser:	Kozuki, Toshiyuki, Hisamoto, Akiko, Tabata, Masahiro, Takigawa, Nagio, Kiura, Katsuyuki, Segawa, Yoshihiko, Nakata, Masao, Mandai, Koichi, Eguchi, Kenji, Ueoka, Hiroshi, Tanimoto, Mitsune
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma Adenocarcinoma - drug therapy Adenocarcinoma - genetics Adenomatosis, Pulmonary - drug therapy Adenomatosis, Pulmonary - genetics Antineoplastic Agents - therapeutic use Atypical adenomatous hyperplasia Biological and medical sciences D761Y Drug Resistance, Neoplasm Epidermal growth factor receptor (EGFR) mutation Exons Female Genes, erbB-1 Genetic Predisposition to Disease Hematology, Oncology and Palliative Medicine Humans Lung neoplasms Lung Neoplasms - drug therapy Lung Neoplasms - genetics Male Medical sciences Multiple lesions Mutation Neoplasms, Multiple Primary - drug therapy Neoplasms, Multiple Primary - genetics Pneumology Pulmonary/Respiratory Quinazolines - therapeutic use Receptor, Epidermal Growth Factor - antagonists & inhibitors Receptor, Epidermal Growth Factor - genetics Retrospective Studies Tumors Tumors of the respiratory system and mediastinum
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