Involvement of p38 MAP kinase in lipopolysaccharide-induced production of pro- and anti-inflammatory cytokines and prostaglandin E(2) in human choriodecidua

Chorioamnionitis is implicated in the pathogenesis of preterm delivery. However, the detailed mechanisms by which infection induces preterm labor are not well understood. This study has assessed the involvement of mitogen-activated protein (MAP) kinases in lipopolysaccharide (LPS)-induced pro- and a...

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Veröffentlicht in:	Journal of reproductive immunology 2007-10, Vol.75 (2), p.82-90
Hauptverfasser:	Shoji, Takako, Yoshida, Souichi, Mitsunari, Masahiro, Miyake, Noriko, Tsukihara, Satoru, Iwabe, Tomio, Harada, Tasuku, Terakawa, Naoki
Format:	Artikel
Sprache:	eng
Schlagworte:	Cyclooxygenase 2 - metabolism Cytokines - metabolism Decidua - metabolism Dinoprostone - metabolism Female Humans Inflammation Mediators - metabolism Lipopolysaccharides - immunology Mitogen-Activated Protein Kinases - antagonists & inhibitors Mitogen-Activated Protein Kinases - metabolism p38 Mitogen-Activated Protein Kinases - antagonists & inhibitors p38 Mitogen-Activated Protein Kinases - metabolism Pregnancy Protein Kinase Inhibitors - pharmacology
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