Speckle-Tracking Radial Strain Reveals Left Ventricular Dyssynchrony in Patients With Permanent Right Ventricular Pacing

Speckle-Tracking Radial Strain Reveals Left Ventricular Dyssynchrony in Patients With Permanent Right Ventricular Pacing Laurens F. Tops, Matthew S. Suffoletto, Gabe B. Bleeker, Eric Boersma, Ernst E. van der Wall, John Gorcsan III, Martin J. Schalij, Jeroen J. Bax In the present study, speckle-trac...

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Veröffentlicht in:Journal of the American College of Cardiology 2007-09, Vol.50 (12), p.1180-1188
Hauptverfasser: Tops, Laurens F., MD, Suffoletto, Matthew S., MD, Bleeker, Gabe B., MD, Boersma, Eric, PhD, van der Wall, Ernst E., MD, Gorcsan, John, MD, Schalij, Martin J., MD, Bax, Jeroen J., MD
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Sprache:eng
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Zusammenfassung:Speckle-Tracking Radial Strain Reveals Left Ventricular Dyssynchrony in Patients With Permanent Right Ventricular Pacing Laurens F. Tops, Matthew S. Suffoletto, Gabe B. Bleeker, Eric Boersma, Ernst E. van der Wall, John Gorcsan III, Martin J. Schalij, Jeroen J. Bax In the present study, speckle-tracking radial strain analysis was used to assess the effects of right ventricular (RV) pacing on the timing of regional left ventricular (LV) wall strain. After long-term RV pacing, a marked heterogeneity in time-to-peak strain among the LV walls was noted, with early activation in the (antero)septal and late activation in the posterolateral segments. In 57% of the patients, this resulted in the presence of LV dyssynchrony with a concomitant worsening in LV function and New York Heart Association functional class. Upgrade to biventricular pacing resulted in partial reversal of these detrimental effects of RV pacing.
ISSN:0735-1097
1558-3597
DOI:10.1016/j.jacc.2007.06.011