Clinical significance of isolated mega cisterna magna
The prevalence and clinical significance of isolated mega cisterna magna in both fetuses and adults is not yet well defined. It is therefore difficult to provide reliable parental counseling in cases of a fetal sonographic diagnosis of this anomaly. The aim of the present study was to, determine the...
Gespeichert in:
| Veröffentlicht in: | Archives of gynecology and obstetrics 2007-11, Vol.276 (5), p.487-490, Article 487 |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 490 |
|---|---|
| container_issue | 5 |
| container_start_page | 487 |
| container_title | Archives of gynecology and obstetrics |
| container_volume | 276 |
| creator | Zimmer, Etan Z Lowenstein, Lior Bronshtein, Moshe Goldsher, Dorith Aharon-Peretz, Judith |
| description | The prevalence and clinical significance of isolated mega cisterna magna in both fetuses and adults is not yet well defined. It is therefore difficult to provide reliable parental counseling in cases of a fetal sonographic diagnosis of this anomaly. The aim of the present study was to, determine the cognitive profile of adults with isolated mega cisterna magna.
We reviewed 19,301 consecutive CT/MRI of the brain. Isolated mega cisterna magna was observed in 49 cases. A battery of neuropsychological tests was performed in 18 adults with this anomaly and in 18 controls who had no brain anomaly on CT/MRI.
Subjects with isolated mega cisterna magna had a lower performance on memory tasks [RAVLT saving score (0.8 +/- 0.2 vs. 1.02 +/- 0.2, P = 0.003)] and verbal fluency [phonemic fluency (9.4 +/- 4.5 vs. 13.6 +/- 5.3, P = 0.02), semantic fluency (19.8 +/- 5.8 vs. 24.4 +/- 7.5, P = 0.05)]. They did not differ from controls in regard to the Raven similarity tests indicating that this brain anomaly is not associated with impairment of general cognitive abilities.
Adults with isolated mega cisterna have an overall normal cognitive functioning but may score inferior to controls on some parameters of memory and verbal fluency. Although application of adult cases to the fetuses is not well established, this information might be of value in parental counseling in cases of a fetus with this anomaly. |
| doi_str_mv | 10.1007/s00404-007-0369-6 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_68272666</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2261893285</sourcerecordid><originalsourceid>FETCH-LOGICAL-c242t-53bc316707b31db8f06a760a8206083f706ebee6b4ffe7c1f9fc2baa55fef4d83</originalsourceid><addsrcrecordid>eNpdkEtLxDAURoMoOo7-ADdSENxVbx69ySxl8AUDbnQd0vRmyNDH2LQL_70tMyC4ylmc-xEOYzccHjiAfkwAClQ-YQ4SVzmesAVXUuSgOT9lC1jNDKgv2GVKOwAujMFzdsG1KqQQYsGKdR3b6F2dpbhtY5iw9ZR1IYupq91AVdbQ1mU-poH61mWN27buip0FVye6Pr5L9vXy_Ll-yzcfr-_rp03uhRJDXsjSS44adCl5VZoA6DSCMwIQjAwakEoiLFUIpD0Pq-BF6VxRBAqqMnLJ7g-7-777HikNtonJU127lroxWTRCC0ScxLt_4q4bp-_WyQqB3EwhTDFZ_GD5vkupp2D3fWxc_2M52LmoPRS1M85F7bx8e1wey4aqv4tjQvkLSrZv6g</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2261893285</pqid></control><display><type>article</type><title>Clinical significance of isolated mega cisterna magna</title><source>MEDLINE</source><source>SpringerLink Journals - AutoHoldings</source><creator>Zimmer, Etan Z ; Lowenstein, Lior ; Bronshtein, Moshe ; Goldsher, Dorith ; Aharon-Peretz, Judith</creator><creatorcontrib>Zimmer, Etan Z ; Lowenstein, Lior ; Bronshtein, Moshe ; Goldsher, Dorith ; Aharon-Peretz, Judith</creatorcontrib><description>The prevalence and clinical significance of isolated mega cisterna magna in both fetuses and adults is not yet well defined. It is therefore difficult to provide reliable parental counseling in cases of a fetal sonographic diagnosis of this anomaly. The aim of the present study was to, determine the cognitive profile of adults with isolated mega cisterna magna.
We reviewed 19,301 consecutive CT/MRI of the brain. Isolated mega cisterna magna was observed in 49 cases. A battery of neuropsychological tests was performed in 18 adults with this anomaly and in 18 controls who had no brain anomaly on CT/MRI.
Subjects with isolated mega cisterna magna had a lower performance on memory tasks [RAVLT saving score (0.8 +/- 0.2 vs. 1.02 +/- 0.2, P = 0.003)] and verbal fluency [phonemic fluency (9.4 +/- 4.5 vs. 13.6 +/- 5.3, P = 0.02), semantic fluency (19.8 +/- 5.8 vs. 24.4 +/- 7.5, P = 0.05)]. They did not differ from controls in regard to the Raven similarity tests indicating that this brain anomaly is not associated with impairment of general cognitive abilities.
Adults with isolated mega cisterna have an overall normal cognitive functioning but may score inferior to controls on some parameters of memory and verbal fluency. Although application of adult cases to the fetuses is not well established, this information might be of value in parental counseling in cases of a fetus with this anomaly.</description><identifier>ISSN: 0932-0067</identifier><identifier>EISSN: 1432-0711</identifier><identifier>DOI: 10.1007/s00404-007-0369-6</identifier><identifier>PMID: 17453222</identifier><language>eng</language><publisher>Germany: Springer Nature B.V</publisher><subject>Adult ; Case-Control Studies ; Cisterna Magna ; Clinical significance ; Cognitive ability ; Dandy-Walker Syndrome - diagnostic imaging ; Dandy-Walker Syndrome - pathology ; Dandy-Walker Syndrome - psychology ; Female ; Fetuses ; Genetic Counseling ; Humans ; Male ; Neuropsychological Tests ; Radiography ; Ultrasonography, Prenatal</subject><ispartof>Archives of gynecology and obstetrics, 2007-11, Vol.276 (5), p.487-490, Article 487</ispartof><rights>Springer-Verlag 2007.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c242t-53bc316707b31db8f06a760a8206083f706ebee6b4ffe7c1f9fc2baa55fef4d83</citedby><cites>FETCH-LOGICAL-c242t-53bc316707b31db8f06a760a8206083f706ebee6b4ffe7c1f9fc2baa55fef4d83</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/17453222$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Zimmer, Etan Z</creatorcontrib><creatorcontrib>Lowenstein, Lior</creatorcontrib><creatorcontrib>Bronshtein, Moshe</creatorcontrib><creatorcontrib>Goldsher, Dorith</creatorcontrib><creatorcontrib>Aharon-Peretz, Judith</creatorcontrib><title>Clinical significance of isolated mega cisterna magna</title><title>Archives of gynecology and obstetrics</title><addtitle>Arch Gynecol Obstet</addtitle><description>The prevalence and clinical significance of isolated mega cisterna magna in both fetuses and adults is not yet well defined. It is therefore difficult to provide reliable parental counseling in cases of a fetal sonographic diagnosis of this anomaly. The aim of the present study was to, determine the cognitive profile of adults with isolated mega cisterna magna.
We reviewed 19,301 consecutive CT/MRI of the brain. Isolated mega cisterna magna was observed in 49 cases. A battery of neuropsychological tests was performed in 18 adults with this anomaly and in 18 controls who had no brain anomaly on CT/MRI.
Subjects with isolated mega cisterna magna had a lower performance on memory tasks [RAVLT saving score (0.8 +/- 0.2 vs. 1.02 +/- 0.2, P = 0.003)] and verbal fluency [phonemic fluency (9.4 +/- 4.5 vs. 13.6 +/- 5.3, P = 0.02), semantic fluency (19.8 +/- 5.8 vs. 24.4 +/- 7.5, P = 0.05)]. They did not differ from controls in regard to the Raven similarity tests indicating that this brain anomaly is not associated with impairment of general cognitive abilities.
Adults with isolated mega cisterna have an overall normal cognitive functioning but may score inferior to controls on some parameters of memory and verbal fluency. Although application of adult cases to the fetuses is not well established, this information might be of value in parental counseling in cases of a fetus with this anomaly.</description><subject>Adult</subject><subject>Case-Control Studies</subject><subject>Cisterna Magna</subject><subject>Clinical significance</subject><subject>Cognitive ability</subject><subject>Dandy-Walker Syndrome - diagnostic imaging</subject><subject>Dandy-Walker Syndrome - pathology</subject><subject>Dandy-Walker Syndrome - psychology</subject><subject>Female</subject><subject>Fetuses</subject><subject>Genetic Counseling</subject><subject>Humans</subject><subject>Male</subject><subject>Neuropsychological Tests</subject><subject>Radiography</subject><subject>Ultrasonography, Prenatal</subject><issn>0932-0067</issn><issn>1432-0711</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2007</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNpdkEtLxDAURoMoOo7-ADdSENxVbx69ySxl8AUDbnQd0vRmyNDH2LQL_70tMyC4ylmc-xEOYzccHjiAfkwAClQ-YQ4SVzmesAVXUuSgOT9lC1jNDKgv2GVKOwAujMFzdsG1KqQQYsGKdR3b6F2dpbhtY5iw9ZR1IYupq91AVdbQ1mU-poH61mWN27buip0FVye6Pr5L9vXy_Ll-yzcfr-_rp03uhRJDXsjSS44adCl5VZoA6DSCMwIQjAwakEoiLFUIpD0Pq-BF6VxRBAqqMnLJ7g-7-777HikNtonJU127lroxWTRCC0ScxLt_4q4bp-_WyQqB3EwhTDFZ_GD5vkupp2D3fWxc_2M52LmoPRS1M85F7bx8e1wey4aqv4tjQvkLSrZv6g</recordid><startdate>200711</startdate><enddate>200711</enddate><creator>Zimmer, Etan Z</creator><creator>Lowenstein, Lior</creator><creator>Bronshtein, Moshe</creator><creator>Goldsher, Dorith</creator><creator>Aharon-Peretz, Judith</creator><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope></search><sort><creationdate>200711</creationdate><title>Clinical significance of isolated mega cisterna magna</title><author>Zimmer, Etan Z ; Lowenstein, Lior ; Bronshtein, Moshe ; Goldsher, Dorith ; Aharon-Peretz, Judith</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c242t-53bc316707b31db8f06a760a8206083f706ebee6b4ffe7c1f9fc2baa55fef4d83</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2007</creationdate><topic>Adult</topic><topic>Case-Control Studies</topic><topic>Cisterna Magna</topic><topic>Clinical significance</topic><topic>Cognitive ability</topic><topic>Dandy-Walker Syndrome - diagnostic imaging</topic><topic>Dandy-Walker Syndrome - pathology</topic><topic>Dandy-Walker Syndrome - psychology</topic><topic>Female</topic><topic>Fetuses</topic><topic>Genetic Counseling</topic><topic>Humans</topic><topic>Male</topic><topic>Neuropsychological Tests</topic><topic>Radiography</topic><topic>Ultrasonography, Prenatal</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Zimmer, Etan Z</creatorcontrib><creatorcontrib>Lowenstein, Lior</creatorcontrib><creatorcontrib>Bronshtein, Moshe</creatorcontrib><creatorcontrib>Goldsher, Dorith</creatorcontrib><creatorcontrib>Aharon-Peretz, Judith</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>Archives of gynecology and obstetrics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Zimmer, Etan Z</au><au>Lowenstein, Lior</au><au>Bronshtein, Moshe</au><au>Goldsher, Dorith</au><au>Aharon-Peretz, Judith</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Clinical significance of isolated mega cisterna magna</atitle><jtitle>Archives of gynecology and obstetrics</jtitle><addtitle>Arch Gynecol Obstet</addtitle><date>2007-11</date><risdate>2007</risdate><volume>276</volume><issue>5</issue><spage>487</spage><epage>490</epage><pages>487-490</pages><artnum>487</artnum><issn>0932-0067</issn><eissn>1432-0711</eissn><abstract>The prevalence and clinical significance of isolated mega cisterna magna in both fetuses and adults is not yet well defined. It is therefore difficult to provide reliable parental counseling in cases of a fetal sonographic diagnosis of this anomaly. The aim of the present study was to, determine the cognitive profile of adults with isolated mega cisterna magna.
We reviewed 19,301 consecutive CT/MRI of the brain. Isolated mega cisterna magna was observed in 49 cases. A battery of neuropsychological tests was performed in 18 adults with this anomaly and in 18 controls who had no brain anomaly on CT/MRI.
Subjects with isolated mega cisterna magna had a lower performance on memory tasks [RAVLT saving score (0.8 +/- 0.2 vs. 1.02 +/- 0.2, P = 0.003)] and verbal fluency [phonemic fluency (9.4 +/- 4.5 vs. 13.6 +/- 5.3, P = 0.02), semantic fluency (19.8 +/- 5.8 vs. 24.4 +/- 7.5, P = 0.05)]. They did not differ from controls in regard to the Raven similarity tests indicating that this brain anomaly is not associated with impairment of general cognitive abilities.
Adults with isolated mega cisterna have an overall normal cognitive functioning but may score inferior to controls on some parameters of memory and verbal fluency. Although application of adult cases to the fetuses is not well established, this information might be of value in parental counseling in cases of a fetus with this anomaly.</abstract><cop>Germany</cop><pub>Springer Nature B.V</pub><pmid>17453222</pmid><doi>10.1007/s00404-007-0369-6</doi><tpages>4</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0932-0067 |
| ispartof | Archives of gynecology and obstetrics, 2007-11, Vol.276 (5), p.487-490, Article 487 |
| issn | 0932-0067 1432-0711 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_68272666 |
| source | MEDLINE; SpringerLink Journals - AutoHoldings |
| subjects | Adult Case-Control Studies Cisterna Magna Clinical significance Cognitive ability Dandy-Walker Syndrome - diagnostic imaging Dandy-Walker Syndrome - pathology Dandy-Walker Syndrome - psychology Female Fetuses Genetic Counseling Humans Male Neuropsychological Tests Radiography Ultrasonography, Prenatal |
| title | Clinical significance of isolated mega cisterna magna |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-26T16%3A30%3A55IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Clinical%20significance%20of%20isolated%20mega%20cisterna%20magna&rft.jtitle=Archives%20of%20gynecology%20and%20obstetrics&rft.au=Zimmer,%20Etan%20Z&rft.date=2007-11&rft.volume=276&rft.issue=5&rft.spage=487&rft.epage=490&rft.pages=487-490&rft.artnum=487&rft.issn=0932-0067&rft.eissn=1432-0711&rft_id=info:doi/10.1007/s00404-007-0369-6&rft_dat=%3Cproquest_cross%3E2261893285%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2261893285&rft_id=info:pmid/17453222&rfr_iscdi=true |