Effects of the serotonin 5-HT2A and 5-HT2C receptor ligands on the discriminative stimulus effects of nicotine in rats

The present study tested the hypothesis that serotonergic (5-HT) 5-HT2A or 5-HT2C receptors or their pharmacological stimulation modulated the discriminative stimulus effects of nicotine in male Wistar rats. To this end the selective 5-HT2A receptor antagonist R-(+)-alpha-(2,3-dimethoxyphenyl)-1-[2-...

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Veröffentlicht in:	European journal of pharmacology 2007-10, Vol.571 (2-3), p.156-165
Hauptverfasser:	ZANIEWSKA, Magdalena, MCCREARY, Andrew C, PRZEGALINSKI, Edmund, FILIP, Malgorzata
Format:	Artikel
Sprache:	eng
Schlagworte:	Aminopyridines - pharmacology Amphetamines - pharmacology Animals Azepines - pharmacology Azetidines - pharmacology Behavior, Animal - drug effects Biological and medical sciences Brain - drug effects Brain - metabolism Discrimination (Psychology) - drug effects Dose-Response Relationship, Drug Ethylamines - pharmacology Fluorobenzenes - pharmacology Indoles - pharmacology Ligands Male Medical sciences Nicotine - pharmacology Nicotinic Agonists - pharmacology Pharmacology. Drug treatments Piperidines - pharmacology Pyridines - pharmacology Rats Rats, Wistar Receptor, Serotonin, 5-HT2A - metabolism Receptor, Serotonin, 5-HT2C - metabolism Receptors, Nicotinic - drug effects Receptors, Nicotinic - metabolism Serotonin 5-HT2 Receptor Agonists Serotonin Antagonists - pharmacology Serotonin Receptor Agonists - pharmacology
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