Fluoride concentrations in dental plaque and saliva after the use of a fluoride dentifrice preceded by a calcium lactate rinse

Plaque fluoride concentrations ([F]) are directly related to plaque calcium concentrations [Ca]. Attempts to increase plaque F uptake from dentifrices or rinses have used methods designed to increase plaque [Ca] but with inconsistent results. This double‐blind, double‐crossover study tested the effe...

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Veröffentlicht in:European journal of oral sciences 2006-12, Vol.114 (6), p.489-493
Hauptverfasser: Pessan, Juliano P., Sicca, Cristina M., De Souza, Tatiana S., Da Silva, Salete M. B., Whitford, Gary M., Buzalaf, Marília A. R.
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container_end_page 493
container_issue 6
container_start_page 489
container_title European journal of oral sciences
container_volume 114
creator Pessan, Juliano P.
Sicca, Cristina M.
De Souza, Tatiana S.
Da Silva, Salete M. B.
Whitford, Gary M.
Buzalaf, Marília A. R.
description Plaque fluoride concentrations ([F]) are directly related to plaque calcium concentrations [Ca]. Attempts to increase plaque F uptake from dentifrices or rinses have used methods designed to increase plaque [Ca] but with inconsistent results. This double‐blind, double‐crossover study tested the effect of a 150 mM calcium lactate rinse used prior to brushing with placebo or fluoridated dentifrices (1030 p.p.m. as NaF) on plaque and salivary [F] and [Ca]. Sixteen children (8–10 yr of age) were randomly assigned to four different groups according to the four treatments (placebo dentifrice or fluoridated dentifrice preceded by calcium lactate or deionized water prerinses). Plaque and saliva were collected 1 and 12 h after brushing on day 7 after starting to use the dentifrices. F was determined using the electrode and Ca was determined using atomic absorption spectrometry. Plaque and salivary [Ca] were not significantly increased after use of the calcium lactate prerinse, except for plaque [Ca] 1 h after the use of the placebo dentifrice. A significant increase in salivary [F] was associated with the calcium lactate prerinse only at 1 h after the use of the fluoridated dentifrice. The the calcium lactate prerinse did not significantly affect plaque [F] under any condition.
doi_str_mv 10.1111/j.1600-0722.2006.00409.x
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source Wiley-Blackwell Journals; MEDLINE
subjects calcium
Calcium - analysis
Calcium Compounds - pharmacokinetics
Cariostatic Agents - therapeutic use
Child
Cross-Over Studies
dental plaque
Dental Plaque - chemistry
Dental Plaque - metabolism
Dental Plaque - prevention & control
Dentifrices - therapeutic use
Dentistry
Double-Blind Method
fluoride
Fluorides - analysis
Humans
Lactates - pharmacokinetics
Linear Models
Mouthwashes - pharmacokinetics
saliva
Saliva - chemistry
Sodium Fluoride - therapeutic use
toothpaste
title Fluoride concentrations in dental plaque and saliva after the use of a fluoride dentifrice preceded by a calcium lactate rinse
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