Enhanced seed phytosterol accumulation through expression of a modified HMG-CoA reductase

The regulation of phytosterol biosynthesis in seeds is of interest to biotechnologists because of the efficacy of dietary phytosterols in reducing blood cholesterol in humans. Mevalonate synthesis via 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoA reductase) is a key step in phytosterol bi...

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Veröffentlicht in:	Plant biotechnology journal 2006-03, Vol.4 (2), p.219-229
Hauptverfasser:	Hey, Sandra J, Powers, Stephen J, Beale, Michael H, Hawkins, Nathaniel D, Ward, Jane L, Halford, Nigel G
Format:	Artikel
Sprache:	eng
Schlagworte:	Arabidopsis Arabidopsis - genetics Arabidopsis thaliana Cauliflower mosaic virus Caulimovirus - genetics Flowers - anatomy & histology Flowers - genetics Flowers - metabolism Genes, Viral Hydroxymethylglutaryl CoA Reductases - genetics Hydroxymethylglutaryl CoA Reductases - metabolism isoprenoids metabolic engineering metabolite signalling Mutation Nicotiana - genetics Phosphorylation phytosterols Phytosterols - biosynthesis Plant Leaves - genetics Plant Leaves - metabolism Plant Proteins - genetics Plant Proteins - metabolism Plants, Genetically Modified - anatomy & histology Plants, Genetically Modified - enzymology Promoter Regions, Genetic Protein Serine-Threonine Kinases - metabolism Recombinant Fusion Proteins - metabolism Seeds - genetics Seeds - metabolism SnRK1 tobacco Transgenes
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