Laboratory and sonographic findings in dialyzed patients with bilateral chronic knee pain versus dialyzed asymptomatic patients
The aim of this study is to evaluate connection of plasma level of beta2-microglobulin, C-reactive protein and uric acid as well as sonographic parameters like thickness of synovial membrane, thickness of femoral condylar cartilage and presence of joint effusion and Baker's cysts with bilateral...
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| Veröffentlicht in: | Collegium antropologicum 2007-06, Vol.31 (2), p.489-494 |
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| container_title | Collegium antropologicum |
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| creator | Barisić, Igor Ljutić, Dragan Vlak, Tonko Bekavac, Josip Janković, Stipan |
| description | The aim of this study is to evaluate connection of plasma level of beta2-microglobulin, C-reactive protein and uric acid as well as sonographic parameters like thickness of synovial membrane, thickness of femoral condylar cartilage and presence of joint effusion and Baker's cysts with bilateral knee pain in dialyzed patients, comparing them with parameters in asymptomatic dialyzed patients. Plasma levels of beta2-microglobulin and C-reactive protein were significantly higher in symptomatic patients while uric acid level showed no difference among the groups. In symptomatic patients synovial membrane was thicker and in those patients there were more knee effusions and Baker's cysts. Thickness of femoral condylar cartilage showed no difference between groups. That suggests that inflammatory mechanisms developing from beta2-microglobulin accumulation could be important factor in bilateral knee pain in dialyzed patients even in shorter duration dialysis. |
| format | Article |
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Plasma levels of beta2-microglobulin and C-reactive protein were significantly higher in symptomatic patients while uric acid level showed no difference among the groups. In symptomatic patients synovial membrane was thicker and in those patients there were more knee effusions and Baker's cysts. Thickness of femoral condylar cartilage showed no difference between groups. That suggests that inflammatory mechanisms developing from beta2-microglobulin accumulation could be important factor in bilateral knee pain in dialyzed patients even in shorter duration dialysis.</description><identifier>ISSN: 0350-6134</identifier><identifier>PMID: 17847928</identifier><language>eng</language><publisher>Croatia</publisher><subject>beta 2-Microglobulin - blood ; Biomarkers - blood ; C-Reactive Protein - metabolism ; Disability ; Diseases ; Humans ; Kidney Failure, Chronic - complications ; Kidney Failure, Chronic - therapy ; Knee Joint - diagnostic imaging ; Medical research ; Pain ; Pain - blood ; Pain - complications ; Pain - diagnostic imaging ; Popliteal Cyst - blood ; Popliteal Cyst - complications ; Popliteal Cyst - diagnostic imaging ; Public health ; Renal Dialysis ; Ultrasonography ; Uric Acid - blood</subject><ispartof>Collegium antropologicum, 2007-06, Vol.31 (2), p.489-494</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/17847928$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Barisić, Igor</creatorcontrib><creatorcontrib>Ljutić, Dragan</creatorcontrib><creatorcontrib>Vlak, Tonko</creatorcontrib><creatorcontrib>Bekavac, Josip</creatorcontrib><creatorcontrib>Janković, Stipan</creatorcontrib><title>Laboratory and sonographic findings in dialyzed patients with bilateral chronic knee pain versus dialyzed asymptomatic patients</title><title>Collegium antropologicum</title><addtitle>Coll Antropol</addtitle><description>The aim of this study is to evaluate connection of plasma level of beta2-microglobulin, C-reactive protein and uric acid as well as sonographic parameters like thickness of synovial membrane, thickness of femoral condylar cartilage and presence of joint effusion and Baker's cysts with bilateral knee pain in dialyzed patients, comparing them with parameters in asymptomatic dialyzed patients. Plasma levels of beta2-microglobulin and C-reactive protein were significantly higher in symptomatic patients while uric acid level showed no difference among the groups. In symptomatic patients synovial membrane was thicker and in those patients there were more knee effusions and Baker's cysts. Thickness of femoral condylar cartilage showed no difference between groups. That suggests that inflammatory mechanisms developing from beta2-microglobulin accumulation could be important factor in bilateral knee pain in dialyzed patients even in shorter duration dialysis.</description><subject>beta 2-Microglobulin - blood</subject><subject>Biomarkers - blood</subject><subject>C-Reactive Protein - metabolism</subject><subject>Disability</subject><subject>Diseases</subject><subject>Humans</subject><subject>Kidney Failure, Chronic - complications</subject><subject>Kidney Failure, Chronic - therapy</subject><subject>Knee Joint - diagnostic imaging</subject><subject>Medical research</subject><subject>Pain</subject><subject>Pain - blood</subject><subject>Pain - complications</subject><subject>Pain - diagnostic imaging</subject><subject>Popliteal Cyst - blood</subject><subject>Popliteal Cyst - complications</subject><subject>Popliteal Cyst - diagnostic imaging</subject><subject>Public health</subject><subject>Renal Dialysis</subject><subject>Ultrasonography</subject><subject>Uric Acid - blood</subject><issn>0350-6134</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2007</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkL1OwzAURjOAaCm8AvLEFsmOYycZUcWfVIkF5ujavmkNiR1sB1QWXp1IFBiZvuWcM3xH2ZJyQXPJeLnITmN8plRUksqTbMGquqyaol5mnxtQPkDyYU_AGRK989sA485q0llnrNtGYh0xFvr9BxoyQrLoUiTvNu2Isj0kDNATvQvezdKLQ5yhWXnDEKf4Z0LcD2PywxzQv5mz7LiDPuL5YVfZ08314_ou3zzc3q-vNvlYlDTlhQTeSNUxg0aVuqlKxmXDlOi0Up1CWleCGVCsQcYbwIKWWjRUawpUgzB8lV1-d8fgXyeMqR1s1Nj34NBPsZV1IepaiH9BLmtGKStm8OIATmpA047BDhD27c-3_AudDXjG</recordid><startdate>200706</startdate><enddate>200706</enddate><creator>Barisić, Igor</creator><creator>Ljutić, Dragan</creator><creator>Vlak, Tonko</creator><creator>Bekavac, Josip</creator><creator>Janković, Stipan</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>8BJ</scope><scope>FQK</scope><scope>JBE</scope><scope>7X8</scope></search><sort><creationdate>200706</creationdate><title>Laboratory and sonographic findings in dialyzed patients with bilateral chronic knee pain versus dialyzed asymptomatic patients</title><author>Barisić, Igor ; Ljutić, Dragan ; Vlak, Tonko ; Bekavac, Josip ; Janković, Stipan</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p240t-26a396bf1dedb4c97413691b5fcbbfbe08751dab19e139ae204c590cc0a0ca5d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2007</creationdate><topic>beta 2-Microglobulin - blood</topic><topic>Biomarkers - blood</topic><topic>C-Reactive Protein - metabolism</topic><topic>Disability</topic><topic>Diseases</topic><topic>Humans</topic><topic>Kidney Failure, Chronic - complications</topic><topic>Kidney Failure, Chronic - therapy</topic><topic>Knee Joint - diagnostic imaging</topic><topic>Medical research</topic><topic>Pain</topic><topic>Pain - blood</topic><topic>Pain - complications</topic><topic>Pain - diagnostic imaging</topic><topic>Popliteal Cyst - blood</topic><topic>Popliteal Cyst - complications</topic><topic>Popliteal Cyst - diagnostic imaging</topic><topic>Public health</topic><topic>Renal Dialysis</topic><topic>Ultrasonography</topic><topic>Uric Acid - blood</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Barisić, Igor</creatorcontrib><creatorcontrib>Ljutić, Dragan</creatorcontrib><creatorcontrib>Vlak, Tonko</creatorcontrib><creatorcontrib>Bekavac, Josip</creatorcontrib><creatorcontrib>Janković, Stipan</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>International Bibliography of the Social Sciences (IBSS)</collection><collection>International Bibliography of the Social Sciences</collection><collection>International Bibliography of the Social Sciences</collection><collection>MEDLINE - Academic</collection><jtitle>Collegium antropologicum</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Barisić, Igor</au><au>Ljutić, Dragan</au><au>Vlak, Tonko</au><au>Bekavac, Josip</au><au>Janković, Stipan</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Laboratory and sonographic findings in dialyzed patients with bilateral chronic knee pain versus dialyzed asymptomatic patients</atitle><jtitle>Collegium antropologicum</jtitle><addtitle>Coll Antropol</addtitle><date>2007-06</date><risdate>2007</risdate><volume>31</volume><issue>2</issue><spage>489</spage><epage>494</epage><pages>489-494</pages><issn>0350-6134</issn><abstract>The aim of this study is to evaluate connection of plasma level of beta2-microglobulin, C-reactive protein and uric acid as well as sonographic parameters like thickness of synovial membrane, thickness of femoral condylar cartilage and presence of joint effusion and Baker's cysts with bilateral knee pain in dialyzed patients, comparing them with parameters in asymptomatic dialyzed patients. Plasma levels of beta2-microglobulin and C-reactive protein were significantly higher in symptomatic patients while uric acid level showed no difference among the groups. In symptomatic patients synovial membrane was thicker and in those patients there were more knee effusions and Baker's cysts. Thickness of femoral condylar cartilage showed no difference between groups. That suggests that inflammatory mechanisms developing from beta2-microglobulin accumulation could be important factor in bilateral knee pain in dialyzed patients even in shorter duration dialysis.</abstract><cop>Croatia</cop><pmid>17847928</pmid><tpages>6</tpages></addata></record> |
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| ispartof | Collegium antropologicum, 2007-06, Vol.31 (2), p.489-494 |
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| language | eng |
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| source | MEDLINE; EZB-FREE-00999 freely available EZB journals |
| subjects | beta 2-Microglobulin - blood Biomarkers - blood C-Reactive Protein - metabolism Disability Diseases Humans Kidney Failure, Chronic - complications Kidney Failure, Chronic - therapy Knee Joint - diagnostic imaging Medical research Pain Pain - blood Pain - complications Pain - diagnostic imaging Popliteal Cyst - blood Popliteal Cyst - complications Popliteal Cyst - diagnostic imaging Public health Renal Dialysis Ultrasonography Uric Acid - blood |
| title | Laboratory and sonographic findings in dialyzed patients with bilateral chronic knee pain versus dialyzed asymptomatic patients |
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