Trisomy 21 as a Sole Acquired Abnormality in an Adult Omani Patient with CD7- and CD9-Positive Acute Myeloid Leukemia

We describe a case of acute myeloid leukemia (AML) in which trisomy 21 was the sole acquired cytogenetic abnormality. The immunophenotype showed positivity for CD7 and CD9 along with CD13, CD33, and CD34. The chromosomal analysis of bone marrow showed 47,XY +21 in all the metaphases analyzed. The co...

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Veröffentlicht in:	Archives of medical research 2007-10, Vol.38 (7), p.797-802
Hauptverfasser:	Udayakumar, Achandira M, Pathare, Anil V, Muralitharan, S, Alghzaly, Asem A, Alkindi, Salam, Raeburn, J.A
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute myeloid leukemia Adult Antigens, CD Antigens, CD7 Antineoplastic Combined Chemotherapy Protocols - therapeutic use Bone Marrow - pathology Cytarabine - administration & dosage Cytogenetic Analysis Cytogenetics Daunorubicin - administration & dosage Down Syndrome - complications Down Syndrome - diagnosis Down Syndrome - genetics Humans Internal Medicine Karyotyping Leukemia, Myeloid, Acute - complications Leukemia, Myeloid, Acute - diagnosis Leukemia, Myeloid, Acute - drug therapy Leukemia, Myeloid, Acute - genetics Male Membrane Glycoproteins Prognosis Remission Induction Tetraspanin-29 Treatment Outcome Trisomy 21
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