A study of soluble HLA-G1 protecting porcine endothelial cells against human natural killer cell-mediated cytotoxicity

Human natural killer (NK) cells, which can mediate direct lysis of porcine endothelial cells, play an important role in xenograft rejection. HLA-G, which is a critical molecule in maintaining maternal immune tolerance of semi-allogenic fetus, is able to protect susceptible target cells from lysis in...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Transplantation proceedings 2006-12, Vol.38 (10), p.3312-3314
Hauptverfasser:	ZENG, M. H, FANG, C. Y, WANG, S. S, ZHU, M, XIE, L, LI, R, WANG, L, WU, X. W, CHEN, S
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals B-Lymphocytes - immunology Biological and medical sciences Cell Line Cloning, Molecular Cytotoxicity, Immunologic DNA, Complementary - genetics Endothelium, Vascular - drug effects Endothelium, Vascular - immunology Fundamental and applied biological sciences. Psychology Fundamental immunology Histocompatibility Antigens Class I - genetics Histocompatibility Antigens Class I - pharmacology HLA Antigens - genetics HLA Antigens - pharmacology HLA-G Antigens Humans Killer Cells, Natural - immunology Medical sciences Models, Animal Reverse Transcriptase Polymerase Chain Reaction Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Swine Tissue, organ and graft immunology Transfection Transplantation, Heterologous - immunology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!