An experimental model for the study of lymphedema and its response to therapeutic lymphangiogenesis

Evaluation of the efficacy of molecular treatment strategies for lymphatic vascular insufficiency requires a suitable preclinical animal model. Ideally, the model should closely replicate the untreated human disease in its pathogenesis and pathological expression. We have undertaken a study of the t...

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Veröffentlicht in:	BioDrugs : clinical immunotherapeutics, biopharmaceuticals, and gene therapy biopharmaceuticals, and gene therapy, 2006-01, Vol.20 (6), p.363-370
Hauptverfasser:	Cheung, Lauren, Han, Jennifer, Beilhack, Andreas, Joshi, Smita, Wilburn, Paul, Dua, Aman, An, Andrew, Rockson, Stanley G
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Disease Animals Disease Models, Animal Female Glycoproteins - metabolism Immunohistochemistry Lymphangiogenesis - drug effects Lymphedema - immunology Lymphedema - metabolism Lymphedema - pathology Lymphedema - therapy Mice Protein Transport Vascular Endothelial Growth Factor A - pharmacology
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