Two Cases of Acute Exacerbation of Interstitial Pneumonia Treated with Polymyxin B-immobilized Fiber Column Hemoperfusion Treatment
The effect of polymixin B-immobilized fiber column (PMX) hemoperfusion treatment for acute exacerbation of interstitial pneumonia (IP) has been reported. Here, we report 2 cases of acute exacerbation of IP successfully treated with PMX hemoperfusion. One is a 55-year-old woman who was diagnosed as m...
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| Veröffentlicht in: | Internal Medicine 2007, Vol.46(17), pp.1447-1454 |
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| container_title | Internal Medicine |
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| creator | Noma, Satoshi Matsuyama, Wataru Mitsuyama, Hideo Suetsugu, Takayuki Koreeda, Yoshimizu Mizuno, Keiko Higashimoto, Ikkou Kakihana, Yasuyuki Hashiguchi, Teruto Maruyama, Ikuro Osame, Mitsuhiro Arimura, Kimiyoshi |
| description | The effect of polymixin B-immobilized fiber column (PMX) hemoperfusion treatment for acute exacerbation of interstitial pneumonia (IP) has been reported. Here, we report 2 cases of acute exacerbation of IP successfully treated with PMX hemoperfusion. One is a 55-year-old woman who was diagnosed as microscopic polyangiitis (MPA) with IP. The other is a 58-year-old man, diagnosed as having idiopathic pulmonary fibrosis. Both cases were treated with PMX hemoperfusion and other therapies. One died on day 44 and the other is still alive. The PMX hemoperfusion treatment decreased the serum levels of several cytokines and activated neutrophil percentage in bronchoalveolar lavage fluid. |
| doi_str_mv | 10.2169/internalmedicine.46.0117 |
| format | Article |
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Here, we report 2 cases of acute exacerbation of IP successfully treated with PMX hemoperfusion. One is a 55-year-old woman who was diagnosed as microscopic polyangiitis (MPA) with IP. The other is a 58-year-old man, diagnosed as having idiopathic pulmonary fibrosis. Both cases were treated with PMX hemoperfusion and other therapies. One died on day 44 and the other is still alive. The PMX hemoperfusion treatment decreased the serum levels of several cytokines and activated neutrophil percentage in bronchoalveolar lavage fluid.</description><identifier>ISSN: 0918-2918</identifier><identifier>EISSN: 1349-7235</identifier><identifier>DOI: 10.2169/internalmedicine.46.0117</identifier><identifier>PMID: 17827847</identifier><language>eng</language><publisher>Japan: The Japanese Society of Internal Medicine</publisher><subject>Anti-Bacterial Agents - therapeutic use ; Bronchoalveolar Lavage Fluid ; bronchoalveolar lavage fluid cells ; CD18+/CD11c ; Fatal Outcome ; Female ; Hemoperfusion - methods ; high mobility group box-1 (HMGB-1) ; Humans ; Lung Diseases, Interstitial - complications ; Lung Diseases, Interstitial - therapy ; Male ; Middle Aged ; Polymyxin B - therapeutic use ; Respiratory Insufficiency - etiology ; Respiratory Insufficiency - therapy ; Treatment Outcome</subject><ispartof>Internal Medicine, 2007, Vol.46(17), pp.1447-1454</ispartof><rights>2007 by The Japanese Society of Internal Medicine</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c525t-d48f041141459d314d85bcd85bb308c970c7f94aa53f4e865080b48111adad643</citedby><cites>FETCH-LOGICAL-c525t-d48f041141459d314d85bcd85bb308c970c7f94aa53f4e865080b48111adad643</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,1877,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/17827847$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Noma, Satoshi</creatorcontrib><creatorcontrib>Matsuyama, Wataru</creatorcontrib><creatorcontrib>Mitsuyama, Hideo</creatorcontrib><creatorcontrib>Suetsugu, Takayuki</creatorcontrib><creatorcontrib>Koreeda, Yoshimizu</creatorcontrib><creatorcontrib>Mizuno, Keiko</creatorcontrib><creatorcontrib>Higashimoto, Ikkou</creatorcontrib><creatorcontrib>Kakihana, Yasuyuki</creatorcontrib><creatorcontrib>Hashiguchi, Teruto</creatorcontrib><creatorcontrib>Maruyama, Ikuro</creatorcontrib><creatorcontrib>Osame, Mitsuhiro</creatorcontrib><creatorcontrib>Arimura, Kimiyoshi</creatorcontrib><title>Two Cases of Acute Exacerbation of Interstitial Pneumonia Treated with Polymyxin B-immobilized Fiber Column Hemoperfusion Treatment</title><title>Internal Medicine</title><addtitle>Intern. Med.</addtitle><description>The effect of polymixin B-immobilized fiber column (PMX) hemoperfusion treatment for acute exacerbation of interstitial pneumonia (IP) has been reported. Here, we report 2 cases of acute exacerbation of IP successfully treated with PMX hemoperfusion. One is a 55-year-old woman who was diagnosed as microscopic polyangiitis (MPA) with IP. The other is a 58-year-old man, diagnosed as having idiopathic pulmonary fibrosis. Both cases were treated with PMX hemoperfusion and other therapies. One died on day 44 and the other is still alive. The PMX hemoperfusion treatment decreased the serum levels of several cytokines and activated neutrophil percentage in bronchoalveolar lavage fluid.</description><subject>Anti-Bacterial Agents - therapeutic use</subject><subject>Bronchoalveolar Lavage Fluid</subject><subject>bronchoalveolar lavage fluid cells</subject><subject>CD18+/CD11c</subject><subject>Fatal Outcome</subject><subject>Female</subject><subject>Hemoperfusion - methods</subject><subject>high mobility group box-1 (HMGB-1)</subject><subject>Humans</subject><subject>Lung Diseases, Interstitial - complications</subject><subject>Lung Diseases, Interstitial - therapy</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Polymyxin B - therapeutic use</subject><subject>Respiratory Insufficiency - etiology</subject><subject>Respiratory Insufficiency - therapy</subject><subject>Treatment Outcome</subject><issn>0918-2918</issn><issn>1349-7235</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2007</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNptkUtr3DAUhUVpaKZp_0LRqjtPJVuy5GU65AWBZDFZC1m-bhT0mEoyyXTbPx67M6RQujkC3e-cC_cghClZ17TtvtlQIAXtPAzW2ABr1q4JpeIdWtGGdZWoG_4erUhHZVXPcoo-5vxESCNFV39Ap1TIWkgmVuj39jnijc6QcRzxuZkK4IsXbSD1utgYlt-bZVsutljt8H2AycdgNd4m0AUG_GzLI76Pbu_3Lzbg75X1PvbW2V_z8NL2kPAmuskHfA0-7iCNU16S__g9hPIJnYzaZfh8fM_Qw-XFdnNd3d5d3WzObyvDa16qgcmRMEoZZbwbGsoGyXuzSN8QaTpBjBg7pjVvRgay5USSnklKqR700LLmDH095O5S_DlBLsrbbMA5HSBOWbWy5pyRdgblATQp5pxgVLtkvU57RYlaClD_FqBYq5YCZuuX446pn4d_jceLz8DdAXjKRf-AN0CnYo2D_yZTcVTKmHgjzaNOCkLzCrLgpp4</recordid><startdate>20070101</startdate><enddate>20070101</enddate><creator>Noma, Satoshi</creator><creator>Matsuyama, Wataru</creator><creator>Mitsuyama, Hideo</creator><creator>Suetsugu, Takayuki</creator><creator>Koreeda, Yoshimizu</creator><creator>Mizuno, Keiko</creator><creator>Higashimoto, Ikkou</creator><creator>Kakihana, Yasuyuki</creator><creator>Hashiguchi, Teruto</creator><creator>Maruyama, Ikuro</creator><creator>Osame, Mitsuhiro</creator><creator>Arimura, Kimiyoshi</creator><general>The Japanese Society of Internal Medicine</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20070101</creationdate><title>Two Cases of Acute Exacerbation of Interstitial Pneumonia Treated with Polymyxin B-immobilized Fiber Column Hemoperfusion Treatment</title><author>Noma, Satoshi ; Matsuyama, Wataru ; Mitsuyama, Hideo ; Suetsugu, Takayuki ; Koreeda, Yoshimizu ; Mizuno, Keiko ; Higashimoto, Ikkou ; Kakihana, Yasuyuki ; Hashiguchi, Teruto ; Maruyama, Ikuro ; Osame, Mitsuhiro ; Arimura, Kimiyoshi</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c525t-d48f041141459d314d85bcd85bb308c970c7f94aa53f4e865080b48111adad643</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2007</creationdate><topic>Anti-Bacterial Agents - therapeutic use</topic><topic>Bronchoalveolar Lavage Fluid</topic><topic>bronchoalveolar lavage fluid cells</topic><topic>CD18+/CD11c</topic><topic>Fatal Outcome</topic><topic>Female</topic><topic>Hemoperfusion - methods</topic><topic>high mobility group box-1 (HMGB-1)</topic><topic>Humans</topic><topic>Lung Diseases, Interstitial - complications</topic><topic>Lung Diseases, Interstitial - therapy</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Polymyxin B - therapeutic use</topic><topic>Respiratory Insufficiency - etiology</topic><topic>Respiratory Insufficiency - therapy</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Noma, Satoshi</creatorcontrib><creatorcontrib>Matsuyama, Wataru</creatorcontrib><creatorcontrib>Mitsuyama, Hideo</creatorcontrib><creatorcontrib>Suetsugu, Takayuki</creatorcontrib><creatorcontrib>Koreeda, Yoshimizu</creatorcontrib><creatorcontrib>Mizuno, Keiko</creatorcontrib><creatorcontrib>Higashimoto, Ikkou</creatorcontrib><creatorcontrib>Kakihana, Yasuyuki</creatorcontrib><creatorcontrib>Hashiguchi, Teruto</creatorcontrib><creatorcontrib>Maruyama, Ikuro</creatorcontrib><creatorcontrib>Osame, Mitsuhiro</creatorcontrib><creatorcontrib>Arimura, Kimiyoshi</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Internal Medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Noma, Satoshi</au><au>Matsuyama, Wataru</au><au>Mitsuyama, Hideo</au><au>Suetsugu, Takayuki</au><au>Koreeda, Yoshimizu</au><au>Mizuno, Keiko</au><au>Higashimoto, Ikkou</au><au>Kakihana, Yasuyuki</au><au>Hashiguchi, Teruto</au><au>Maruyama, Ikuro</au><au>Osame, Mitsuhiro</au><au>Arimura, Kimiyoshi</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Two Cases of Acute Exacerbation of Interstitial Pneumonia Treated with Polymyxin B-immobilized Fiber Column Hemoperfusion Treatment</atitle><jtitle>Internal Medicine</jtitle><addtitle>Intern. Med.</addtitle><date>2007-01-01</date><risdate>2007</risdate><volume>46</volume><issue>17</issue><spage>1447</spage><epage>1454</epage><pages>1447-1454</pages><issn>0918-2918</issn><eissn>1349-7235</eissn><abstract>The effect of polymixin B-immobilized fiber column (PMX) hemoperfusion treatment for acute exacerbation of interstitial pneumonia (IP) has been reported. Here, we report 2 cases of acute exacerbation of IP successfully treated with PMX hemoperfusion. One is a 55-year-old woman who was diagnosed as microscopic polyangiitis (MPA) with IP. The other is a 58-year-old man, diagnosed as having idiopathic pulmonary fibrosis. Both cases were treated with PMX hemoperfusion and other therapies. One died on day 44 and the other is still alive. 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| ispartof | Internal Medicine, 2007, Vol.46(17), pp.1447-1454 |
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| source | MEDLINE; J-STAGE (Japan Science & Technology Information Aggregator, Electronic) Freely Available Titles - Japanese |
| subjects | Anti-Bacterial Agents - therapeutic use Bronchoalveolar Lavage Fluid bronchoalveolar lavage fluid cells CD18+/CD11c Fatal Outcome Female Hemoperfusion - methods high mobility group box-1 (HMGB-1) Humans Lung Diseases, Interstitial - complications Lung Diseases, Interstitial - therapy Male Middle Aged Polymyxin B - therapeutic use Respiratory Insufficiency - etiology Respiratory Insufficiency - therapy Treatment Outcome |
| title | Two Cases of Acute Exacerbation of Interstitial Pneumonia Treated with Polymyxin B-immobilized Fiber Column Hemoperfusion Treatment |
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